Daily Papers

Large Language Models (LLMs) are fluent but prone to hallucinations, producing answers that appear plausible yet are unsupported by available evidence. This failure is especially problematic in high-stakes domains where decisions must be justified by verifiable information. We introduce EvidenceRL, a reinforcement learning framework that enforces evidence adherence during training. EvidenceRL scores candidate responses for grounding (entailment with retrieved evidence and context) and correctness (agreement with reference answers) and optimizes the generator using Group Relative Policy Optimization (GRPO). We evaluate across two high-stakes domains, cardiac diagnosis and legal reasoning, where EvidenceRL consistently improves evidence grounding and faithfulness without sacrificing task accuracy. On cardiac diagnosis, F1@3 increases from 37.0 to 54.5 on Llama-3.2-3B while grounding (G_{max}@3) rises from 47.6 to 78.2; hallucinations drop nearly 5times and evidence-supported diagnoses increase from 31.8\% to 61.6\%. On legal reasoning, EvidenceRL raises Faithfulness from 32.8\% to 67.6\% on Llama-3.1-8B, demonstrating consistent behavioral change across domains. Our code is open-sourced at https://github.com/Wizaaard/EvidenceRL.git.

This study quantifies the association between non-adherence to antipsychotic medications and adverse outcomes in individuals with schizophrenia. We frame the problem using survival analysis, focusing on the time to the earliest of several adverse events (early death, involuntary hospitalization, jail booking). We extend standard causal inference methods (T-learner, S-learner, nearest neighbor matching) to utilize various survival models to estimate individual and average treatment effects, where treatment corresponds to medication non-adherence. Analyses are repeated using different amounts of longitudinal information (3, 6, 9, and 12 months). Using data from Allegheny County in western Pennsylvania, we find strong evidence that non-adherence advances adverse outcomes by approximately 1 to 4 months. Ablation studies confirm that county-provided risk scores adjust for key confounders, as their removal amplifies the estimated effects. Subgroup analyses by medication formulation (injectable vs. oral) and medication type consistently show that non-adherence is associated with earlier adverse events. These findings highlight the clinical importance of adherence in delaying psychiatric crises and show that integrating survival analysis with causal inference tools can yield policy-relevant insights. We caution that although we apply causal inference, we only make associative claims and discuss assumptions needed for causal interpretation.

Large language models in regulated financial workflows are governed by natural-language policies that the same model interprets, creating a principal--agent failure: outputs can appear compliant without being compliant. Existing evaluation measures task accuracy but not whether governance constrains behaviour at the decision rationale level -- where regulated decisions must be auditable. We introduce five governance metrics that quantify policy compliance at the rationale level and apply them in a synthetic banking domain to compare text-only governance against mechanical enforcement: four primitives operating outside the model's interpretive loop. Under text-only governance, 27% of deferrals carry no decision-relevant information. Mechanical enforcement reduces this rate by 73%, more than doubles deferral information content, and raises task accuracy from MCC~0.43 to 0.88. The improvement is driven by architectural separation: LLM-generated rationales under mechanical enforcement show comparable CDL to text-only governance -- the gain comes from removing clear-cut decisions from the model's control. A causal ablation confirms that each primitive is individually necessary. Our central finding is a governance-task decoupling: under structural stress, text-only governance degrades on both dimensions simultaneously, whereas mechanical enforcement preserves governance quality even as task performance drops. This implies that governance and task evaluation are distinct axes: accuracy is not a sufficient proxy for governance in regulated AI systems.

Tool use has become central to modern LLM agents, yet interface design is rarely isolated as an experimental variable. This paper studies whether schema based tool contracts and structured validation diagnostics improve reliability under strict interaction budgets. We evaluate three conditions that preserve identical tool semantics and information content: free form documentation, JSON Schema specifications, and JSON Schema with structured diagnostics. We implement a deterministic software engineering sandbox with logs, metrics, configurations, and repository tasks, and evaluate a fully crossed pilot with one open local model, three seeds, three interface conditions, and four budgets. We report end task success, interface misuse, execution failures, semantic misuse, recovery behavior, and overhead. In this pilot, success remains zero across conditions, while schema conditions reduce interface misuse but not semantic misuse. The evidence supports a precise interpretation that interface formalization improves contract adherence, but semantic action quality and timeout sensitive tasks remain dominant bottlenecks under constrained local inference.

Simulating high-fidelity patients offers a powerful avenue for studying complex diseases while addressing the challenges of fragmented, biased, and privacy-restricted real-world data. In this study, we introduce SynthAgent, a novel Multi-Agent System (MAS) framework designed to model obesity patients with comorbid mental disorders, including depression, anxiety, social phobia, and binge eating disorder. SynthAgent integrates clinical and medical evidence from claims data, population surveys, and patient-centered literature to construct personalized virtual patients enriched with personality traits that influence adherence, emotion regulation, and lifestyle behaviors. Through autonomous agent interactions, the system simulates disease progression, treatment response, and life management across diverse psychosocial contexts. Evaluation of more than 100 generated patients demonstrated that GPT-5 and Claude 4.5 Sonnet achieved the highest fidelity as the core engine in the proposed MAS framework, outperforming Gemini 2.5 Pro and DeepSeek-R1. SynthAgent thus provides a scalable and privacy-preserving framework for exploring patient journeys, behavioral dynamics, and decision-making processes in both medical and psychological domains.

Large Vision-Language Models (LVLMs) have demonstrated impressive general capabilities across a wide range of multi-modal tasks. However, the reasoning processes of LVLMs often suffer from unreliable outputs and limited interpretability. To address this, grounded visual reasoning has emerged as a promising paradigm that enforces responses anchored on salient visual evidence regions. However, existing approaches typically rely on costly supervision such as bounding box annotations, chain-of-thought rationale or external tool calls, limiting their scalability. In this work, we propose Ground-R1, a reinforcement learning framework that enables grounded visual reasoning without requiring explicit evidence or rationale annotations. Ground-R1 consists of a grounding phase that generates evidence region rollouts based on format constraints, and an answering phase that produces responses guided by both answer correctness and format adherence rewards. Extensive experiments across multiple visual reasoning benchmarks manifest that Ground-R1 achieves superior performance and exhibits emergent cognitive behaviors such as uncertainty awareness, spatial perception, and iterative refinement, offering a scalable and interpretable alternative to existing approaches.

We present MedXIAOHE, a medical vision-language foundation model designed to advance general-purpose medical understanding and reasoning in real-world clinical applications. MedXIAOHE achieves state-of-the-art performance across diverse medical benchmarks and surpasses leading closed-source multimodal systems on multiple capabilities. To achieve this, we propose an entity-aware continual pretraining framework that organizes heterogeneous medical corpora to broaden knowledge coverage and reduce long-tail gaps (e.g., rare diseases). For medical expert-level reasoning and interaction, MedXIAOHE incorporates diverse medical reasoning patterns via reinforcement learning and tool-augmented agentic training, enabling multi-step diagnostic reasoning with verifiable decision traces. To improve reliability in real-world use, MedXIAOHE integrates user-preference rubrics, evidence-grounded reasoning, and low-hallucination long-form report generation, with improved adherence to medical instructions. We release this report to document our practical design choices, scaling insights, and evaluation framework, hoping to inspire further research.

Although much research has focused on AI explanations to support decisions in complex information-seeking tasks such as fact-checking, the role of evidence is surprisingly under-researched. In our study, we systematically varied explanation type, AI prediction certainty, and correctness of AI system advice for non-expert participants, who evaluated the veracity of claims and AI system predictions. Participants were provided the option of easily inspecting the underlying evidence. We found that participants consistently relied on evidence to validate AI claims across all experimental conditions. When participants were presented with natural language explanations, evidence was used less frequently although they relied on it when these explanations seemed insufficient or flawed. Qualitative data suggests that participants attempted to infer evidence source reliability, despite source identities being deliberately omitted. Our results demonstrate that evidence is a key ingredient in how people evaluate the reliability of information presented by an AI system and, in combination with natural language explanations, offers valuable support for decision-making. Further research is urgently needed to understand how evidence ought to be presented and how people engage with it in practice.

Clinical LLMs are often scaled by increasing model size, context length, retrieval complexity, or inference-time compute, with the implicit expectation that higher accuracy implies safer behavior. This assumption is incomplete in medicine, where a few confident, high-risk, or evidence-contradicting errors can matter more than average benchmark performance. We introduce SaFE-Scale, a framework for measuring how clinical LLM safety changes across model scale, evidence quality, retrieval strategy, context exposure, and inference-time compute. To instantiate this framework, we introduce RadSaFE-200, a Radiology Safety-Focused Evaluation benchmark of 200 multiple-choice questions with clinician-defined clean evidence, conflict evidence, and option-level labels for high-risk error, unsafe answer, and evidence contradiction. We evaluated 34 locally deployed LLMs across six deployment conditions: closed-book prompting (zero-shot), clean evidence, conflict evidence, standard RAG, agentic RAG, and max-context prompting. Clean evidence produced the strongest improvement, increasing mean accuracy from 73.5% to 94.1%, while reducing high-risk error from 12.0% to 2.6%, contradiction from 12.7% to 2.3%, and dangerous overconfidence from 8.0% to 1.6%. Standard RAG and agentic RAG did not reproduce this safety profile: agentic RAG improved accuracy over standard RAG and reduced contradiction, but high-risk error and dangerous overconfidence remained elevated. Max-context prompting increased latency without closing the safety gap, and additional inference-time compute produced only limited gains. Worst-case analysis showed that clinically consequential errors concentrated in a small subset of questions. Clinical LLM safety is therefore not a passive consequence of scaling, but a deployment property shaped by evidence quality, retrieval design, context construction, and collective failure behavior.

Recent benchmarks have probed factual consistency and rhetorical robustness in Large Language Models (LLMs). However, a knowledge gap exists regarding how directional framing of factually true statements influences model agreement, a common scenario for LLM users. AssertBench addresses this by sampling evidence-supported facts from FEVEROUS, a fact verification dataset. For each (evidence-backed) fact, we construct two framing prompts: one where the user claims the statement is factually correct, and another where the user claims it is incorrect. We then record the model's agreement and reasoning. The desired outcome is that the model asserts itself, maintaining consistent truth evaluation across both framings, rather than switching its evaluation to agree with the user. AssertBench isolates framing-induced variability from the model's underlying factual knowledge by stratifying results based on the model's accuracy on the same claims when presented neutrally. In doing so, this benchmark aims to measure an LLM's ability to "stick to its guns" when presented with contradictory user assertions about the same fact. The complete source code is available at https://github.com/achowd32/assert-bench.

Evidence-grounded reasoning requires more than attaching retrieved text to a prediction: a model should make decisions that depend on whether the provided evidence supports the target claim. In practice, this often fails because supervision is weak, evidence is only loosely tied to the claim, and evaluation does not test evidence dependence directly. We introduce case-grounded evidence verification, a general framework in which a model receives a local case context, external evidence, and a structured claim, and must decide whether the evidence supports the claim for that case. Our key contribution is a supervision construction procedure that generates explicit support examples together with semantically controlled non-support examples, including counterfactual wrong-state and topic-related negatives, without manual evidence annotation. We instantiate the framework in radiology and train a standard verifier on the resulting support task. The learned verifier substantially outperforms both case-only and evidence-only baselines, remains strong under correct evidence, and collapses when evidence is removed or swapped, indicating genuine evidence dependence. This behavior transfers across unseen evidence articles and an external case distribution, though performance degrades under evidence-source shift and remains sensitive to backbone choice. Overall, the results suggest that a major bottleneck in evidence grounding is not only model capacity, but the lack of supervision that encodes the causal role of evidence.

Recent large language models often answer factual questions correctly. But users can't trust any given claim a model makes without fact-checking, because language models can hallucinate convincing nonsense. In this work we use reinforcement learning from human preferences (RLHP) to train "open-book" QA models that generate answers whilst also citing specific evidence for their claims, which aids in the appraisal of correctness. Supporting evidence is drawn from multiple documents found via a search engine, or from a single user-provided document. Our 280 billion parameter model, GopherCite, is able to produce answers with high quality supporting evidence and abstain from answering when unsure. We measure the performance of GopherCite by conducting human evaluation of answers to questions in a subset of the NaturalQuestions and ELI5 datasets. The model's response is found to be high-quality 80\% of the time on this Natural Questions subset, and 67\% of the time on the ELI5 subset. Abstaining from the third of questions for which it is most unsure improves performance to 90\% and 80\% respectively, approaching human baselines. However, analysis on the adversarial TruthfulQA dataset shows why citation is only one part of an overall strategy for safety and trustworthiness: not all claims supported by evidence are true.

Machine learning systems in fraud detection, credit scoring, and clinical risk assessment operate under delayed ground truth: outcome labels arrive days to months after the decision they evaluate. During this blind period, governance evidence degrades through mechanisms that neither drift detection methods nor governance frameworks adequately address. This paper formalizes an evidence sufficiency model with four dimensions (completeness, freshness, reliability, representativeness) and a decision-readiness gate that quantifies how label latency degrades evidence quality. The model maps three drift types to dimension-specific degradation trajectories. A complementary proxy indicator framework comprising seven measurement categories estimates sufficiency degradation without labels, with explicit coverage mapping and characterized blind spots per drift type. Evaluation on the IEEE-CIS Fraud Detection dataset (~590K transactions) with controlled drift injection shows that composite proxy monitoring detects covariate and mixed drift with 100% detection rate, while concept drift without feature change remains undetected -- consistent with the theoretical impossibility of unsupervised detection when P(X) is unchanged. Blind period simulation confirms monotone sufficiency degradation, with concept drift degrading fastest (S=0.242 at day 60 vs 0.418 for no-drift). The framework contributes a governance sufficiency monitoring instrument; its value lies in translating drift signals into auditable sufficiency assessments with characterized blind spots. Mapping sufficiency levels to governance actions requires deployment-specific calibration beyond this study's scope.

How do we most effectively treat a disease or condition? Ideally, we could consult a database of evidence gleaned from clinical trials to answer such questions. Unfortunately, no such database exists; clinical trial results are instead disseminated primarily via lengthy natural language articles. Perusing all such articles would be prohibitively time-consuming for healthcare practitioners; they instead tend to depend on manually compiled systematic reviews of medical literature to inform care. NLP may speed this process up, and eventually facilitate immediate consult of published evidence. The Evidence Inference dataset was recently released to facilitate research toward this end. This task entails inferring the comparative performance of two treatments, with respect to a given outcome, from a particular article (describing a clinical trial) and identifying supporting evidence. For instance: Does this article report that chemotherapy performed better than surgery for five-year survival rates of operable cancers? In this paper, we collect additional annotations to expand the Evidence Inference dataset by 25\%, provide stronger baseline models, systematically inspect the errors that these make, and probe dataset quality. We also release an abstract only (as opposed to full-texts) version of the task for rapid model prototyping. The updated corpus, documentation, and code for new baselines and evaluations are available at http://evidence-inference.ebm-nlp.com/.

The ability of large language models (LLMs) to follow user instructions is central to their reliability, safety, and usefulness. While prior studies assess instruction adherence in the model's main responses, we argue that it is also critical for large reasoning models (LRMs) to follow user instructions throughout their reasoning process. Reasoning instruction following makes LRMs more controllable and transparent, while reducing risks of undesirable shortcuts, hallucinations, or reward hacking within reasoning traces. To evaluate this dimension, we introduce ReasonIF, a systematic benchmark for assessing reasoning instruction following. ReasonIF includes six categories of instruction prompts, spanning multilingual reasoning, formatting and length control. Across many open-source LRMs including GPT-OSS, Qwen3, and DeepSeek-R1, we find substantial failures in reasoning instruction adherence: the highest instruction following score (IFS) remains below 0.25, meaning that fewer than 25% of reasoning traces comply with the given instructions. Notably, as task difficulty increases, reasoning instruction following degrades further. We also explore two strategies to enhance reasoning instruction fidelity. (1) multi-turn reasoning and (2) Reasoning Instruction Finetuning (RIF) using synthetic data. RIF improves the IFS of GPT-OSS-20B from 0.11 to 0.27, indicating measurable progress but leaving ample room for improvement.

Large Reasoning Models (LRMs) exhibit strong performance, yet often produce rationales that sound plausible but fail to reflect their true decision process, undermining reliability and trust. We introduce a formal framework for reasoning faithfulness, defined by two testable conditions: stance consistency (a coherent stance linking reasoning to answer) and causal influence (the stated reasoning causally drives the answer under output-level interventions), explicitly decoupled from accuracy. To operationalize this, we present RFEval, a benchmark of 7,186 instances across seven tasks that probes faithfulness via controlled, output-level counterfactual interventions. Evaluating twelve open-source LRMs, we find unfaithfulness in 49.7% of outputs, predominantly from stance inconsistency. Failures are concentrated in brittle, convergent domains such as math and code, and correlate more with post-training regimes than with scale: within-family ablations indicate that adding current RL-style objectives on top of supervised fine-tuning can reduce reasoning faithfulness, even when accuracy is maintained. Crucially, accuracy is neither a sufficient nor a reliable proxy for faithfulness: once controlling for model and task, the accuracy-faithfulness link is weak and statistically insignificant. Our work establishes a rigorous methodology for auditing LRM reliability and shows that trustworthy AI requires optimizing not only for correct outcomes but also for the structural integrity of the reasoning process. Our code and dataset can be found at project page: https://aidaslab.github.io/RFEval/}{https://aidaslab.github.io/RFEval/

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with structured protocols. We study this gap using Written Exposure Therapy (WET) guidelines as a testbed. In evaluating model responses to curated clinician-vetted questions, we find that errors persist even when authoritative passages are provided. To address this, we propose an evaluation framework that measures accuracy, consistency, and fidelity of reasoning. Our results highlight both the potential and the risks: retrieval-augmented generation (RAG) can constrain outputs, but safe deployment requires assessing reasoning as rigorously as retrieval.

Adherence to prescribed treatments is crucial for individuals with chronic conditions to avoid costly or adverse health outcomes. For certain patient groups, intensive lifestyle interventions are vital for enhancing medication adherence. Accurate forecasting of treatment adherence can open pathways to developing an on-demand intervention tool, enabling timely and personalized support. With the increasing popularity of smartphones and wearables, it is now easier than ever to develop and deploy smart activity monitoring systems. However, effective forecasting systems for treatment adherence based on wearable sensors are still not widely available. We close this gap by proposing Adherence Forecasting and Intervention with Machine Intelligence (AIMI). AIMI is a knowledge-guided adherence forecasting system that leverages smartphone sensors and previous medication history to estimate the likelihood of forgetting to take a prescribed medication. A user study was conducted with 27 participants who took daily medications to manage their cardiovascular diseases. We designed and developed CNN and LSTM-based forecasting models with various combinations of input features and found that LSTM models can forecast medication adherence with an accuracy of 0.932 and an F-1 score of 0.936. Moreover, through a series of ablation studies involving convolutional and recurrent neural network architectures, we demonstrate that leveraging known knowledge about future and personalized training enhances the accuracy of medication adherence forecasting. Code available: https://github.com/ab9mamun/AIMI.

The scholarly publishing ecosystem faces a dual crisis of unmanageable submission volumes and unregulated AI, creating an urgent need for new governance models to safeguard scientific integrity. The traditional human-only peer review regime lacks a scalable, objective benchmark, making editorial processes opaque and difficult to audit. Here we investigate a deterministic simulation framework that provides the first stable, evidence-based standard for evaluating AI-generated peer review reports. Analyzing 352 peer-review simulation reports, we identify consistent system state indicators that demonstrate its reliability. First, the system is able to simulate calibrated editorial judgment, with 'Revise' decisions consistently forming the majority outcome (>50%) across all disciplines, while 'Reject' rates dynamically adapt to field-specific norms, rising to 45% in Health Sciences. Second, it maintains unwavering procedural integrity, enforcing a stable 29% evidence-anchoring compliance rate that remains invariant across diverse review tasks and scientific domains. These findings demonstrate a system that is predictably rule-bound, mitigating the stochasticity of generative AI. For the scientific community, this provides a transparent tool to ensure fairness; for publishing strategists, it offers a scalable instrument for auditing workflows, managing integrity risks, and implementing evidence-based governance. The framework repositions AI as an essential component of institutional accountability, providing the critical infrastructure to maintain trust in scholarly communication.

Multimodal Large Language Models (MLLMs) have significantly advanced document understanding, yet current Doc-VQA evaluations score only the final answer and leave the supporting evidence unchecked. This answer-only approach masks a critical failure mode: a model can land on the correct answer while grounding it in the wrong passage -- a critical risk in high-stakes domains like law, finance, and medicine, where every conclusion must be traceable to a specific source region. To address this, we introduce CiteVQA, a benchmark that requires models to return element-level bounding-box citations alongside each answer, evaluating both jointly. CiteVQA comprises 1,897 questions across 711 PDFs spanning seven domains and two languages, averaging 40.6 pages per document. To ensure fidelity and scalability, the ground-truth citations are generated by an automated pipeline-which identifies crucial evidence via masking ablation-and are subsequently validated through expert review. At the core of our evaluation is Strict Attributed Accuracy (SAA), which credits a prediction only when the answer and the cited region are both correct. Auditing 20 MLLMs reveals a pervasive Attribution Hallucination: models frequently produce the right answer while citing the wrong region. The strongest system (Gemini-3.1-Pro-Preview) achieves an SAA of only 76.0, and the strongest open-source MLLM reaches just 22.5. Ultimately, towards trustworthy document intelligence, CiteVQA exposes a reliability gap that answer-only evaluations overlook, providing the instrumentation needed to close it. Our repository is available at https://github.com/opendatalab/CiteVQA.

Observational studies can yield clinically actionable evidence at scale, but executing them on real-world databases is open-ended and requires coherent decisions across cohort construction, analysis, and reporting. Prior evaluations of LLM agents emphasize isolated steps or single answers, missing the integrity and internal structure of the resulting evidence bundle. To address this gap, we introduce RWE-bench, a benchmark grounded in MIMIC-IV and derived from peer-reviewed observational studies. Each task provides the corresponding study protocol as the reference standard, requiring agents to execute experiments in a real database and iteratively generate tree-structured evidence bundles. We evaluate six LLMs (three open-source, three closed-source) under three agent scaffolds using both question-level correctness and end-to-end task metrics. Across 162 tasks, task success is low: the best agent reaches 39.9%, and the best open-source model reaches 30.4%. Agent scaffolds also matter substantially, causing over 30% variation in performance metrics. Furthermore, we implement an automated cohort evaluation method to rapidly localize errors and identify agent failure modes. Overall, the results highlight persistent limitations in agents' ability to produce end-to-end evidence bundles, and efficient validation remains an important direction for future work. Code and data are available at https://github.com/somewordstoolate/RWE-bench.

Seeking health-related advice on the internet has become a common practice in the digital era. Determining the trustworthiness of medical claims found online and finding appropriate evidence for this information is increasingly challenging. Fact-checking has emerged as an approach to assess the veracity of factual claims using evidence from credible knowledge sources. To help advance the automation of this task, in this paper, we introduce a novel dataset of 750 health-related claims, labeled for veracity by medical experts and backed with evidence from appropriate clinical studies. We provide an analysis of the dataset, highlighting its characteristics and challenges. The dataset can be used for Machine Learning tasks related to automated fact-checking such as evidence retrieval, veracity prediction, and explanation generation. For this purpose, we provide baseline models based on different approaches, examine their performance, and discuss the findings.

As language models shift from single-shot answer generation toward multi-step reasoning that retrieves and consumes evidence mid-inference, evaluating the role of individual retrieved items becomes more important. Existing RAG evaluation typically targets final-answer quality, citation faithfulness, or answer-level attribution, but none of these directly targets the intervention-based, per-evidence-item utility view we study here. We introduce CUE-R, a lightweight intervention-based framework for measuring per-evidence-item operational utility in single-shot RAG using shallow observable retrieval-use traces. CUE-R perturbs individual evidence items via REMOVE, REPLACE, and DUPLICATE operators, then measures changes along three utility axes (correctness, proxy-based grounding faithfulness, and confidence error) plus a trace-divergence signal. We also outline an operational evidence-role taxonomy for interpreting intervention outcomes. Experiments on HotpotQA and 2WikiMultihopQA with Qwen-3 8B and GPT-5.2 reveal a consistent pattern: REMOVE and REPLACE substantially harm correctness and grounding while producing large trace shifts, whereas DUPLICATE is often answer-redundant yet not fully behaviorally neutral. A zero-retrieval control confirms that these effects arise from degradation of meaningful retrieval. A two-support ablation further shows that multi-hop evidence items can interact non-additively: removing both supports harms performance far more than either single removal. Our results suggest that answer-only evaluation misses important evidence effects and that intervention-based utility analysis is a practical complement for RAG evaluation.

We introduce the Agent GPA (Goal-Plan-Action) framework: an evaluation paradigm based on an agent's operational loop of setting goals, devising plans, and executing actions. The framework includes five evaluation metrics: Goal Fulfillment, Logical Consistency, Execution Efficiency, Plan Quality, and Plan Adherence. Logical Consistency checks that an agent's actions are consistent with its prior actions. Execution Efficiency checks whether the agent executes in the most efficient way to achieve its goal. Plan Quality checks whether an agent's plans are aligned with its goals; Plan Adherence checks if an agent's actions are aligned with its plan; and Goal Fulfillment checks that agent's final outcomes match the stated goals. Our experimental results on two benchmark datasets - the public TRAIL/GAIA dataset and an internal dataset for a production-grade data agent - show that this framework (a) provides a systematic way to cover a broad range of agent failures, including all agent errors on the TRAIL/GAIA benchmark dataset; (b) supports LLM-judges that exhibit strong agreement with human annotation, covering 80% to over 95% errors; and (c) localizes errors with 86% agreement to enable targeted improvement of agent performance.

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few studies implemented and evaluated RAG in downstream domain-specific applications. We developed a RAG pipeline with 70,000 ophthalmology-specific documents that retrieve relevant documents to augment LLMs during inference time. In a case study on long-form consumer health questions, we systematically evaluated the responses including over 500 references of LLMs with and without RAG on 100 questions with 10 healthcare professionals. The evaluation focuses on factuality of evidence, selection and ranking of evidence, attribution of evidence, and answer accuracy and completeness. LLMs without RAG provided 252 references in total. Of which, 45.3% hallucinated, 34.1% consisted of minor errors, and 20.6% were correct. In contrast, LLMs with RAG significantly improved accuracy (54.5% being correct) and reduced error rates (18.8% with minor hallucinations and 26.7% with errors). 62.5% of the top 10 documents retrieved by RAG were selected as the top references in the LLM response, with an average ranking of 4.9. The use of RAG also improved evidence attribution (increasing from 1.85 to 2.49 on a 5-point scale, P<0.001), albeit with slight decreases in accuracy (from 3.52 to 3.23, P=0.03) and completeness (from 3.47 to 3.27, P=0.17). The results demonstrate that LLMs frequently exhibited hallucinated and erroneous evidence in the responses, raising concerns for downstream applications in the medical domain. RAG substantially reduced the proportion of such evidence but encountered challenges.

We consider the problem of performing Bayesian inference in probabilistic models where observations are accompanied by uncertainty, referred to as "uncertain evidence." We explore how to interpret uncertain evidence, and by extension the importance of proper interpretation as it pertains to inference about latent variables. We consider a recently-proposed method "distributional evidence" as well as revisit two older methods: Jeffrey's rule and virtual evidence. We devise guidelines on how to account for uncertain evidence and we provide new insights, particularly regarding consistency. To showcase the impact of different interpretations of the same uncertain evidence, we carry out experiments in which one interpretation is defined as "correct." We then compare inference results from each different interpretation illustrating the importance of careful consideration of uncertain evidence.

Equipping agents with the capacity to justify made decisions using supporting evidence represents a cornerstone of accountable decision-making. Furthermore, ensuring that justifications are in line with human expectations and societal norms is vital, especially in high-stakes situations such as healthcare. In this work, we propose the use of a debate-based reward model for reinforcement learning agents, where the outcome of a zero-sum debate game quantifies the justifiability of a decision in a particular state. This reward model is then used to train a justifiable policy, whose decisions can be more easily corroborated with supporting evidence. In the debate game, two argumentative agents take turns providing supporting evidence for two competing decisions. Given the proposed evidence, a proxy of a human judge evaluates which decision is better justified. We demonstrate the potential of our approach in learning policies for prescribing and justifying treatment decisions of septic patients. We show that augmenting the reward with the feedback signal generated by the debate-based reward model yields policies highly favored by the judge when compared to the policy obtained solely from the environment rewards, while hardly sacrificing any performance. Moreover, in terms of the overall performance and justifiability of trained policies, the debate-based feedback is comparable to the feedback obtained from an ideal judge proxy that evaluates decisions using the full information encoded in the state. This suggests that the debate game outputs key information contained in states that is most relevant for evaluating decisions, which in turn substantiates the practicality of combining our approach with human-in-the-loop evaluations. Lastly, we showcase that agents trained via multi-agent debate learn to propose evidence that is resilient to refutations and closely aligns with human preferences.

Self-consistency has emerged as a popular technique for improving large language model accuracy on reasoning tasks. The approach is straightforward: generate multiple reasoning paths and select the most common answer through majority voting. While this reliably boosts accuracy, it remains unclear whether these gains reflect genuine improvements in reasoning quality. We investigate a fundamental question that has not been studied before: does inference scaling improve reasoning faithfulness? We conduct a comprehensive empirical study across four frontier models (GPT-5.2, Claude Opus 4.5, Gemini-3-flash-preview, and DeepSeek-v3.2) on 100 GSM8K mathematical reasoning problems. Our analysis employs bootstrap confidence intervals, McNemar's tests for paired comparisons, and Cohen's d effect sizes to quantify the effects rigorously. The results reveal striking differences across models that challenge common assumptions about self-consistency. GPT-5.2 shows the expected pattern: accuracy improves from 78% to 90% at N=5, with faithfulness remaining relatively stable (0.540 to 0.510). Claude Opus 4.5 tells a completely different story. Its accuracy actually drops from 78% to 74.3% while faithfulness jumps dramatically from 0.270 to 0.891 at N=5. DeepSeek-v3.2, already at 98% accuracy, shows ceiling effects with modest faithfulness gains (0.440 to 0.541). Gemini-3-flash improves from 81% to 86% accuracy with a slight faithfulness decrease (0.260 to 0.212). Problem difficulty analysis reveals that GPT-5.2 solves 82% of hard problems while breaking only 13% of easy ones. Claude, in contrast, breaks 23% of easy problems, explaining its accuracy decrease. These findings matter for practitioners: self-consistency is not universally beneficial, and teams should test their specific models before deployment. We release our code and provide practical recommendations for navigating these tradeoffs.

Large language model (LLM)-based systems are increasingly deployed to conduct scientific research autonomously, yet whether their reasoning adheres to the epistemic norms that make scientific inquiry self-correcting is poorly understood. Here, we evaluate LLM-based scientific agents across eight domains, spanning workflow execution to hypothesis-driven inquiry, through more than 25,000 agent runs and two complementary lenses: (i) a systematic performance analysis that decomposes the contributions of the base model and the agent scaffold, and (ii) a behavioral analysis of the epistemological structure of agent reasoning. We observe that the base model is the primary determinant of both performance and behavior, accounting for 41.4% of explained variance versus 1.5% for the scaffold. Across all configurations, evidence is ignored in 68% of traces, refutation-driven belief revision occurs in 26%, and convergent multi-test evidence is rare. The same reasoning pattern appears whether the agent executes a computational workflow or conducts hypothesis-driven inquiry. They persist even when agents receive near-complete successful reasoning trajectories as context, and the resulting unreliability compounds across repeated trials in epistemically demanding domains. Thus, current LLM-based agents execute scientific workflows but do not exhibit the epistemic patterns that characterize scientific reasoning. Outcome-based evaluation cannot detect these failures, and scaffold engineering alone cannot repair them. Until reasoning itself becomes a training target, the scientific knowledge produced by such agents cannot be justified by the process that generated it.

This paper describes the results of SemEval 2023 task 7 -- Multi-Evidence Natural Language Inference for Clinical Trial Data (NLI4CT) -- consisting of 2 tasks, a Natural Language Inference (NLI) task, and an evidence selection task on clinical trial data. The proposed challenges require multi-hop biomedical and numerical reasoning, which are of significant importance to the development of systems capable of large-scale interpretation and retrieval of medical evidence, to provide personalized evidence-based care. Task 1, the entailment task, received 643 submissions from 40 participants, and Task 2, the evidence selection task, received 364 submissions from 23 participants. The tasks are challenging, with the majority of submitted systems failing to significantly outperform the majority class baseline on the entailment task, and we observe significantly better performance on the evidence selection task than on the entailment task. Increasing the number of model parameters leads to a direct increase in performance, far more significant than the effect of biomedical pre-training. Future works could explore the limitations of large models for generalization and numerical inference, and investigate methods to augment clinical datasets to allow for more rigorous testing and to facilitate fine-tuning. We envisage that the dataset, models, and results of this task will be useful to the biomedical NLI and evidence retrieval communities. The dataset, competition leaderboard, and website are publicly available.

Finding relevant literature underpins the practice of evidence-based medicine. From 2014 to 2016, TREC conducted a clinical decision support track, wherein participants were tasked with finding articles relevant to clinical questions posed by physicians. In total, 87 teams have participated over the past three years, generating 395 runs. During this period, each team has trialled a variety of methods. While there was significant overlap in the methods employed by different teams, the results were varied. Due to the diversity of the platforms used, the results arising from the different techniques are not directly comparable, reducing the ability to build on previous work. By using a stable platform, we have been able to compare different document and query processing techniques, allowing us to experiment with different search parameters. We have used our system to reproduce leading teams runs, and compare the results obtained. By benchmarking our indexing and search techniques, we can statistically test a variety of hypotheses, paving the way for further research.

Users increasingly rely on Large Language Models (LLMs) for Deep Research, using them to synthesize diverse sources into structured reports that support understanding and action. In this context, the practical reliability of such reports hinges on logical quality: whether the report's claims and arguments are explicitly supported and can be trusted as a basis for downstream use, rather than merely appearing fluent or informative. However, current evaluation frameworks largely overlook this requirement. To bridge this gap, we introduce ReportLogic, a benchmark that quantifies report-level logical quality through a reader-centric lens of auditability. Specifically, ReportLogic adopts a hierarchical taxonomy that evaluates whether readers can (1) trace an on-topic report structure with a unified analytical arc (Macro-Logic), (2) understand the progression with necessary context (Expositional-Logic), and (3) verify conclusions via explicit claim--support (Structural-Logic). Based on this taxonomy, we construct a human-annotated rubric-guided dataset and train an open-source LogicJudge for scalable evaluation. We further evaluate judge robustness via adversarial attacks, showing that off-the-shelf LLM judges are frequently influenced by superficial cues (e.g., verbosity), and reasoning modes can mask broken support relations. Overall, our results provide actionable guidance for building more robust logic evaluators and improving the logical reliability of LLM-generated reports.

The increasing adoption of large language models (LLMs) has been accompanied by growing concerns regarding their reliability and trustworthiness. As a result, a growing body of research focuses on evidence-based text generation with LLMs, aiming to link model outputs to supporting evidence to ensure traceability and verifiability. However, the field is fragmented due to inconsistent terminology, isolated evaluation practices, and a lack of unified benchmarks. To bridge this gap, we systematically analyze 134 papers, introduce a unified taxonomy of evidence-based text generation with LLMs, and investigate 300 evaluation metrics across seven key dimensions. Thereby, we focus on approaches that use citations, attribution, or quotations for evidence-based text generation. Building on this, we examine the distinctive characteristics and representative methods in the field. Finally, we highlight open challenges and outline promising directions for future work.

Retrieval-Augmented Generation (RAG) is the prevailing paradigm for grounding Large Language Models (LLMs), yet the mechanisms governing how models integrate groups of conflicting retrieved evidence remain opaque. Does an LLM answer a certain way because the evidence is factually strong, because of a prior belief, or merely because it is repeated frequently? To answer this, we introduce GroupQA, a curated dataset of 1,635 controversial questions paired with 15,058 diversely-sourced evidence documents, annotated for stance and qualitative strength. Through controlled experiments, we characterize group-level evidence aggregation dynamics: Paraphrasing an argument can be more persuasive than providing distinct independent support; Models favor evidence presented first rather than last, and Larger models are increasingly resistant to adapt to presented evidence. Additionally, we find that LLM explanations to group-based answers are unfaithful. Together, we show that LLMs behave consistently as vulnerable heuristic followers, with direct implications for improving RAG system design.

LLMs are increasingly used as long-running conversational agents, yet every major benchmark evaluating their memory treats user information as static facts to be stored and retrieved. That's the wrong model. People change their minds, and over extended interactions, phenomena like opinion drift, over-alignment, and confirmation bias start to matter a lot. BeliefShift introduces a longitudinal benchmark designed specifically to evaluate belief dynamics in multi-session LLM interactions. It covers three tracks: Temporal Belief Consistency, Contradiction Detection, and Evidence-Driven Revision. The dataset includes 2,400 human-annotated multi-session interaction trajectories spanning health, politics, personal values, and product preferences. We evaluate seven models including GPT-4o, Claude 3.5 Sonnet, Gemini 1.5 Pro, LLaMA-3, and Mistral-Large under zero-shot and retrieval-augmented generation (RAG) settings. Results reveal a clear trade-off: models that personalize aggressively resist drift poorly, while factually grounded models miss legitimate belief updates. We further introduce four novel evaluation metrics: Belief Revision Accuracy (BRA), Drift Coherence Score (DCS), Contradiction Resolution Rate (CRR), and Evidence Sensitivity Index (ESI).

AI scientist systems are increasingly deployed for autonomous research, yet their academic integrity has never been systematically evaluated. We introduce SCIINTEGRITY-BENCH, the first benchmark designed around a dilemmatic evaluation paradigm: each of its 33 scenarios across 11 trap categories is constructed so that honest acknowledgment of failure is the only correct response, while task completion requires misconduct. Across 231 evaluation runs spanning 7 state-of-the-art LLMs, the overall integrity problem rate reaches 34.2%, and no model achieves zero failures. Most strikingly, across missing-data scenarios, all seven models generate synthetic data rather than acknowledging infeasibility, differing only in whether they disclose the substitution. A further prompt ablation study separates two drivers: removing explicit completion pressure sharply reduces undisclosed fabrication from 20.6% to 3.2%, while the underlying synthesis rate remains unchanged, revealing an intrinsic completion bias that persists independent of prompt-level instructions. These findings point to the absence of honest refusal as a trained disposition as the primary driver of observed failures. We release SCIINTEGRITY-BENCH at https://github.com/liuxingtong/Sci-Integrity-Bench.

This study presents PARROT (Persuasion and Agreement Robustness Rating of Output Truth), a robustness focused framework designed to measure the degradation in accuracy that occurs under social pressure exerted on users through authority and persuasion in large language models (LLMs) the phenomenon of sycophancy (excessive conformity). PARROT (i) isolates causal effects by comparing the neutral version of the same question with an authoritatively false version using a double-blind evaluation, (ii) quantifies confidence shifts toward the correct and imposed false responses using log-likelihood-based calibration tracking, and (iii) systematically classifies failure modes (e.g., robust correct, sycophantic agreement, reinforced error, stubborn error, self-correction, etc.) using an eight-state behavioral taxonomy. We evaluated 22 models using 1,302 MMLU-style multiple-choice questions across 13 domains and domain-specific authority templates. Findings show marked heterogeneity: advanced models (e.g., GPT-5, GPT-4.1, Claude Sonnet 4.5) exhibit low "follow rates" (leq 11%, GPT-5: 4\%) and minimal accuracy loss, while older/smaller models show severe epistemic collapse (GPT-4: 80\%, Qwen 2.5-1.5B: 94\%). The danger is not limited to response changes; weak models reduce confidence in the correct response while increasing confidence in the imposed incorrect response. While international law and global knowledge at the domain level exhibit high fragility, elementary mathematics is relatively resilient. Consequently, we argue that the goal of "resistance to overfitting pressure" should be addressed as a primary objective alongside accuracy, harm avoidance, and privacy for safe deployment in the real world.

Chain-of-thought (CoT) reasoning has been proposed as a transparency mechanism for large language models in safety-critical deployments, yet its effectiveness depends on faithfulness (whether models accurately verbalize the factors that actually influence their outputs), a property that prior evaluations have examined in only two proprietary models, finding acknowledgment rates as low as 25% for Claude 3.7 Sonnet and 39% for DeepSeek-R1. To extend this evaluation across the open-weight ecosystem, this study tests 12 open-weight reasoning models spanning 9 architectural families (7B-685B parameters) on 498 multiple-choice questions from MMLU and GPQA Diamond, injecting six categories of reasoning hints (sycophancy, consistency, visual pattern, metadata, grader hacking, and unethical information) and measuring the rate at which models acknowledge hint influence in their CoT when hints successfully alter answers. Across 41,832 inference runs, overall faithfulness rates range from 39.7% (Seed-1.6-Flash) to 89.9% (DeepSeek-V3.2-Speciale) across model families, with consistency hints (35.5%) and sycophancy hints (53.9%) exhibiting the lowest acknowledgment rates. Training methodology and model family predict faithfulness more strongly than parameter count, and keyword-based analysis reveals a striking gap between thinking-token acknowledgment (approximately 87.5%) and answer-text acknowledgment (approximately 28.6%), suggesting that models internally recognize hint influence but systematically suppress this acknowledgment in their outputs. These findings carry direct implications for the viability of CoT monitoring as a safety mechanism and suggest that faithfulness is not a fixed property of reasoning models but varies systematically with architecture, training method, and the nature of the influencing cue.

Corruption studies, the primary tool for evaluating chain-of-thought (CoT) faithfulness, identify which chain positions are "computationally important" by measuring accuracy when steps are replaced with errors. We identify a systematic confound: for chains with explicit terminal answer statements, the dominant format in standard benchmarks, corruption studies detect where the answer text appears, not where computation occurs. A within-dataset format ablation provides the key evidence: on standard GSM8K chains ending with "the answer is X," removing only the answer statement, preserving all reasoning, collapses suffix sensitivity ~19x at 3B (N=300, p=0.022). Conflicting-answer experiments quantify the causal mechanism: at 7B, CC accuracy drops to near-zero (<=0.02) across five architecture families; the followed-wrong rate spans 0.63-1.00 at 3B-7B and attenuates at larger scales (0.300 at Phi-4-14B, ~0.01 at 32B). A within-stable 7B replication (9.3x attenuation, N=76, p=7.8e-3; Qwen3-8B N=299, p=0.004) provides converging evidence, and the pattern replicates on MATH (DeepSeek-R1-7B: 10.9x suffix-survival recovery). On chains without answer suffixes the same protocol identifies the prefix as load-bearing (Delta=-0.77, p<10^-12). Generation-time probes confirm a dissociation: the answer is not early-determined during generation (early commitment <5%), yet at consumption time model outputs systematically follow the explicit answer text. The format-determination effect persists through 14B (8.5x ratio, p=0.001) and converges toward zero at 32B. We propose a three-prerequisite protocol (question-only control, format characterization, all-position sweep) as a minimum standard for corruption-based faithfulness studies.

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented generation (RAG) has been widely adopted to address these limitations by supplementing model outputs with retrieved evidence. However, whether RAG reliably achieves these goals remains unclear. Here, we present the most comprehensive expert evaluation of RAG in medicine to date. Eighteen medical experts contributed a total of 80,502 annotations, assessing 800 model outputs generated by GPT-4o and Llama-3.1-8B across 200 real-world patient and USMLE-style queries. We systematically decomposed the RAG pipeline into three components: (i) evidence retrieval (relevance of retrieved passages), (ii) evidence selection (accuracy of evidence usage), and (iii) response generation (factuality and completeness of outputs). Contrary to expectation, standard RAG often degraded performance: only 22% of top-16 passages were relevant, evidence selection remained weak (precision 41-43%, recall 27-49%), and factuality and completeness dropped by up to 6% and 5%, respectively, compared with non-RAG variants. Retrieval and evidence selection remain key failure points for the model, contributing to the overall performance drop. We further show that simple yet effective strategies, including evidence filtering and query reformulation, substantially mitigate these issues, improving performance on MedMCQA and MedXpertQA by up to 12% and 8.2%, respectively. These findings call for re-examining RAG's role in medicine and highlight the importance of stage-aware evaluation and deliberate system design for reliable medical LLM applications.

With the widespread adoption of large language models (LLMs), hallucinations, which are non-factual fabrications in model outputs, have become serious concerns. Reasoning capabilities have received attention as a self-verification process to improve output reliability. However, the effect of reasoning within a closed system where LLMs cannot rely on external tools or knowledge has yet to be clarified. We therefore conduct experiments under strict constraints (recommending peer-reviewed journal articles in computer science) to examine the effect of reasoning across multiple models (GPT-5.2 and Gemini 3 Flash). Our results reveal a problematic trade-off between constraint compliance and factual accuracy. Non-reasoning models exhibit high constraint violation rates (66-75%) but maintain factual accuracy, while reasoning models reduce violations (13-26%) but systematically distort known facts to satisfy constraints and increase complete fabrication. This trade-off pattern is consistent across both models despite different architectures, indicating a fundamental limitation of reasoning. Furthermore, reasoning does not uniformly improve output authenticity: effects diverge by model, reflecting different allocations of the compliance-truthfulness trade-off. These findings challenge the assumption that reasoning universally improves reliability: reasoning models trade honest constraint violations for detection-resistant distortions.

Background: Large language models (LLMs) are trained to follow directions, but this introduces a vulnerability to blindly comply with user requests even if they generate wrong information. In medicine, this could accelerate the generation of misinformation that impacts human well-being. Objectives/Methods: We analyzed compliance to requests to generate misleading content about medications in settings where models know the request is illogical. We investigated whether in-context directions and instruction-tuning of LLMs to prioritize logical reasoning over compliance reduced misinformation risk. Results: While all frontier LLMs complied with misinformation requests, both prompt-based and parameter-based approaches can improve the detection of logic flaws in requests and prevent the dissemination of medical misinformation. Conclusion: Shifting LLMs to prioritize logic over compliance could reduce risks of exploitation for medical misinformation.

Vision-language models (VLMs) often produce chain-of-thought (CoT) explanations that sound plausible yet fail to reflect the underlying decision process, undermining trust in high-stakes clinical use. Existing evaluations rarely catch this misalignment, prioritizing answer accuracy or adherence to formats. We present a clinically grounded framework for chest X-ray visual question answering (VQA) that probes CoT faithfulness via controlled text and image modifications across three axes: clinical fidelity, causal attribution, and confidence calibration. In a reader study (n=4), evaluator-radiologist correlations fall within the observed inter-radiologist range for all axes, with strong alignment for attribution (Kendall's tau_b=0.670), moderate alignment for fidelity (tau_b=0.387), and weak alignment for confidence tone (tau_b=0.091), which we report with caution. Benchmarking six VLMs shows that answer accuracy and explanation quality are decoupled, acknowledging injected cues does not ensure grounding, and text cues shift explanations more than visual cues. While some open-source models match final answer accuracy, proprietary models score higher on attribution (25.0% vs. 1.4%) and often on fidelity (36.1% vs. 31.7%), highlighting deployment risks and the need to evaluate beyond final answer accuracy.

Peer review in machine learning is under growing pressure from rising submission volume and limited reviewer time. Most LLM-based reviewing systems read only the manuscript and generate comments from the paper's own narrative. This makes their outputs sensitive to presentation quality and leaves them weak when the evidence needed for review lies in related work or released code. We present FactReview, an evidence-grounded reviewing system that combines claim extraction, literature positioning, and execution-based claim verification. Given a submission, FactReview identifies major claims and reported results, retrieves nearby work to clarify the paper's technical position, and, when code is available, executes the released repository under bounded budgets to test central empirical claims. It then produces a concise review and an evidence report that assigns each major claim one of five labels: Supported, Supported by the paper, Partially supported, In conflict, or Inconclusive. In a case study on CompGCN, FactReview reproduces results that closely match those reported for link prediction and node classification, yet also shows that the paper's broader performance claim across tasks is not fully sustained: on MUTAG graph classification, the reproduced result is 88.4%, whereas the strongest baseline reported in the paper remains 92.6%. The claim is therefore only partially supported. More broadly, this case suggests that AI is most useful in peer review not as a final decision-maker, but as a tool for gathering evidence and helping reviewers produce more evidence-grounded assessments. The code is public at https://github.com/DEFENSE-SEU/Review-Assistant.

Recent progress in multimodal large language models (MLLMs) has demonstrated promising performance on medical benchmarks and in preliminary trials as clinical assistants. Yet, our pilot audit of diagnostic cases uncovers a critical failure mode: instability in early evidence interpretation precedes hallucination, creating branching reasoning trajectories that cascade into globally inconsistent conclusions. This highlights the need for clinical reasoning agents that constrain stochasticity and hallucination while producing auditable decision flows. We introduce MedMMV, a controllable multimodal multi-agent framework for reliable and verifiable clinical reasoning. MedMMV stabilizes reasoning through diversified short rollouts, grounds intermediate steps in a structured evidence graph under the supervision of a Hallucination Detector, and aggregates candidate paths with a Combined Uncertainty scorer. On six medical benchmarks, MedMMV improves accuracy by up to 12.7% and, more critically, demonstrates superior reliability. Blind physician evaluations confirm that MedMMV substantially increases reasoning truthfulness without sacrificing informational content. By controlling instability through a verifiable, multi-agent process, our framework provides a robust path toward deploying trustworthy AI systems in high-stakes domains like clinical decision support.

Deep Research Agents (DRAs) generate citation-rich reports via multi-step search and synthesis, yet existing benchmarks mainly target text-only settings or short-form multimodal QA, missing end-to-end multimodal evidence use. We introduce MMDeepResearch-Bench (MMDR-Bench), a benchmark of 140 expert-crafted tasks across 21 domains, where each task provides an image-text bundle to evaluate multimodal understanding and citation-grounded report generation. Compared to prior setups, MMDR-Bench emphasizes report-style synthesis with explicit evidence use, where models must connect visual artifacts to sourced claims and maintain consistency across narrative, citations, and visual references. We further propose a unified, interpretable evaluation pipeline: Formula-LLM Adaptive Evaluation (FLAE) for report quality, Trustworthy Retrieval-Aligned Citation Evaluation (TRACE) for citation-grounded evidence alignment, and Multimodal Support-Aligned Integrity Check (MOSAIC) for text-visual integrity, each producing fine-grained signals that support error diagnosis beyond a single overall score. Experiments across 25 state-of-the-art models reveal systematic trade-offs between generation quality, citation discipline, and multimodal grounding, highlighting that strong prose alone does not guarantee faithful evidence use and that multimodal integrity remains a key bottleneck for deep research agents.

Randomized controlled trials (RCTs) are the benchmark for causal inference, yet field implementation can deviate. We here present a remote audit - a design-based, preregistrable diagnostic that uses only pre-treatment satellite imagery to test whether assignment is independent of local conditions. The conditional randomization test of the remote audit evaluates whether treatment assignment is more predictable from pre-treatment satellite features than expected under the experiment's registered mechanism, providing a finite-sample valid, design-based diagnostic that requires no parametric assumptions. The procedure is finite-sample valid, honors blocks and clusters, and controls multiplicity across image models and resolutions via a max-statistic. We illustrate with two RCTs: Uganda's Youth Opportunities Program, where the audit corroborates randomization and flags selection and missing-data risks; and a school-based trial in Bangladesh, where assignment is highly predictable from pre-treatment features relative to the stated design, consistent with independent concerns about irregularities. Remote audits complement balance tests, lower early-stage costs, and enable rapid design checks when baseline surveys are expensive or infeasible.

This position paper argues that AI-assisted software engineering requires explicit mechanisms for tracking the epistemic status and temporal validity of architectural decisions. LLM coding assistants generate decisions faster than teams can validate them, yet no widely-adopted framework distinguishes conjecture from verified knowledge, prevents trust inflation through conservative aggregation, or detects when evidence expires. We propose three requirements for responsible AI-assisted engineering: (1) epistemic layers that separate unverified hypotheses from empirically validated claims, (2) conservative assurance aggregation grounded in the Gödel t-norm that prevents weak evidence from inflating confidence, and (3) automated evidence decay tracking that surfaces stale assumptions before they cause failures. We formalize these requirements as the First Principles Framework (FPF), ground its aggregation semantics in fuzzy logic, and define a quintet of invariants that any valid aggregation operator must satisfy. Our retrospective audit applying FPF criteria to two internal projects found that 20-25% of architectural decisions had stale evidence within two months, validating the need for temporal accountability. We outline research directions including learnable aggregation operators, federated evidence sharing, and SMT-based claim validation.

Evaluating whether multimodal large language models truly understand long-form scientific papers remains challenging: answer-only metrics and synthetic "Needle-In-A-Haystack" tests often reward answer matching without requiring a causal, evidence-linked reasoning trace in the document. We propose the "Fish-in-the-Ocean" (FITO) paradigm, which requires models to construct explicit cross-modal evidence chains within native scientific documents. To operationalize FITO, we build SIN-Data, a scientific interleaved corpus that preserves the native interleaving of text and figures. On top of it, we construct SIN-Bench with four progressive tasks covering evidence discovery (SIN-Find), hypothesis verification (SIN-Verify), grounded QA (SIN-QA), and evidence-anchored synthesis (SIN-Summary). We further introduce "No Evidence, No Score", scoring predictions when grounded to verifiable anchors and diagnosing evidence quality via matching, relevance, and logic. Experiments on eight MLLMs show that grounding is the primary bottleneck: Gemini-3-pro achieves the best average overall score (0.573), while GPT-5 attains the highest SIN-QA answer accuracy (0.767) but underperforms on evidence-aligned overall scores, exposing a gap between correctness and traceable support.

Qualitative research faces a critical reliability challenge: traditional inter-rater agreement methods require multiple human coders, are time-intensive, and often yield moderate consistency. We present a multi-perspective validation framework for LLM-based thematic analysis that combines ensemble validation with dual reliability metrics: Cohen's Kappa (κ) for inter-rater agreement and cosine similarity for semantic consistency. Our framework enables configurable analysis parameters (1-6 seeds, temperature 0.0-2.0), supports custom prompt structures with variable substitution, and provides consensus theme extraction across any JSON format. As proof-of-concept, we evaluate three leading LLMs (Gemini 2.5 Pro, GPT-4o, Claude 3.5 Sonnet) on a psychedelic art therapy interview transcript, conducting six independent runs per model. Results demonstrate Gemini achieves highest reliability (κ= 0.907, cosine=95.3%), followed by GPT-4o (κ= 0.853, cosine=92.6%) and Claude (κ= 0.842, cosine=92.1%). All three models achieve a high agreement (κ> 0.80), validating the multi-run ensemble approach. The framework successfully extracts consensus themes across runs, with Gemini identifying 6 consensus themes (50-83% consistency), GPT-4o identifying 5 themes, and Claude 4 themes. Our open-source implementation provides researchers with transparent reliability metrics, flexible configuration, and structure-agnostic consensus extraction, establishing methodological foundations for reliable AI-assisted qualitative research.

Explanations for AI models in high-stakes domains like medicine often lack verifiability, which can hinder trust. To address this, we propose an interactive agent that produces explanations through an auditable sequence of actions. The agent learns a policy to strategically seek external visual evidence to support its diagnostic reasoning. This policy is optimized using reinforcement learning, resulting in a model that is both efficient and generalizable. Our experiments show that this action-based reasoning process significantly improves calibrated accuracy, reducing the Brier score by 18\% compared to a non-interactive baseline. To validate the faithfulness of the agent's explanations, we introduce a causal intervention method. By masking the visual evidence the agent chooses to use, we observe a measurable degradation in its performance (DeltaBrier=+0.029), confirming that the evidence is integral to its decision-making process. Our work provides a practical framework for building AI systems with verifiable and faithful reasoning capabilities.

Providing high quality explanations for AI predictions based on machine learning is a challenging and complex task. To work well it requires, among other factors: selecting a proper level of generality/specificity of the explanation; considering assumptions about the familiarity of the explanation beneficiary with the AI task under consideration; referring to specific elements that have contributed to the decision; making use of additional knowledge (e.g. expert evidence) which might not be part of the prediction process; and providing evidence supporting negative hypothesis. Finally, the system needs to formulate the explanation in a clearly interpretable, and possibly convincing, way. Given these considerations, ANTIDOTE fosters an integrated vision of explainable AI, where low-level characteristics of the deep learning process are combined with higher level schemes proper of the human argumentation capacity. ANTIDOTE will exploit cross-disciplinary competences in deep learning and argumentation to support a broader and innovative view of explainable AI, where the need for high-quality explanations for clinical cases deliberation is critical. As a first result of the project, we publish the Antidote CasiMedicos dataset to facilitate research on explainable AI in general, and argumentation in the medical domain in particular.

Scientific research relies on accurate citation for attribution and integrity, yet large language models (LLMs) introduce a new risk: fabricated references that appear plausible but correspond to no real publications. Such hallucinated citations have already been observed in submissions and accepted papers at major machine learning venues, exposing vulnerabilities in peer review. Meanwhile, rapidly growing reference lists make manual verification impractical, and existing automated tools remain fragile to noisy and heterogeneous citation formats and lack standardized evaluation. We present the first comprehensive benchmark and detection framework for hallucinated citations in scientific writing. Our multi-agent verification pipeline decomposes citation checking into claim extraction, evidence retrieval, passage matching, reasoning, and calibrated judgment to assess whether a cited source truly supports its claim. We construct a large-scale human-validated dataset across domains and define unified metrics for citation faithfulness and evidence alignment. Experiments with state-of-the-art LLMs reveal substantial citation errors and show that our framework significantly outperforms prior methods in both accuracy and interpretability. This work provides the first scalable infrastructure for auditing citations in the LLM era and practical tools to improve the trustworthiness of scientific references.

Large language models (LLMs) can explain their predictions through post-hoc or Chain-of-Thought (CoT) explanations. But an LLM could make up reasonably sounding explanations that are unfaithful to its underlying reasoning. Recent work has designed tests that aim to judge the faithfulness of post-hoc or CoT explanations. In this work we argue that these faithfulness tests do not measure faithfulness to the models' inner workings -- but rather their self-consistency at output level. Our contributions are three-fold: i) We clarify the status of faithfulness tests in view of model explainability, characterising them as self-consistency tests instead. This assessment we underline by ii) constructing a Comparative Consistency Bank for self-consistency tests that for the first time compares existing tests on a common suite of 11 open LLMs and 5 tasks -- including iii) our new self-consistency measure CC-SHAP. CC-SHAP is a fine-grained measure (not a test) of LLM self-consistency. It compares how a model's input contributes to the predicted answer and to generating the explanation. Our fine-grained CC-SHAP metric allows us iii) to compare LLM behaviour when making predictions and to analyse the effect of other consistency tests at a deeper level, which takes us one step further towards measuring faithfulness by bringing us closer to the internals of the model than strictly surface output-oriented tests. Our code is available at https://github.com/Heidelberg-NLP/CC-SHAP

AI agents deployed as persistent assistants must maintain correct beliefs as their information environment evolves. In practice, evidence is scattered across heterogeneous sources that often contradict one another, new information can invalidate earlier conclusions, and user preferences surface through corrections rather than explicit instructions. Existing benchmarks largely assume static, single-authority settings and do not evaluate whether agents can keep up with this complexity. We introduce ClawArena, a benchmark for evaluating AI agents in evolving information environments. Each scenario maintains a complete hidden ground truth while exposing the agent only to noisy, partial, and sometimes contradictory traces across multi-channel sessions, workspace files, and staged updates. Evaluation is organized around three coupled challenges: multi-source conflict reasoning, dynamic belief revision, and implicit personalization, whose interactions yield a 14-category question taxonomy. Two question formats, multi-choice (set-selection) and shell-based executable checks, test both reasoning and workspace grounding. The current release contains 64 scenarios across 8 professional domains, totaling 1{,}879 evaluation rounds and 365 dynamic updates. Experiments on five agent frameworks and five language models show that both model capability (15.4% range) and framework design (9.2%) substantially affect performance, that self-evolving skill frameworks can partially close model-capability gaps, and that belief revision difficulty is determined by update design strategy rather than the mere presence of updates. Code is available at https://github.com/aiming-lab/ClawArena.

As LLM-based agents are deployed in production systems, understanding their behavioral consistency (whether they produce similar action sequences when given identical tasks) becomes critical for reliability. We study consistency in the context of SWE-bench, a challenging software engineering benchmark requiring complex, multi-step reasoning. Comparing Claude~4.5~Sonnet, GPT-5, and Llama-3.1-70B across 50 runs each (10 tasks times 5 runs), we find that across models, higher consistency aligns with higher accuracy: Claude achieves the lowest variance (CV: 15.2\%) and highest accuracy (58\%), GPT-5 is intermediate (CV: 32.2\%, accuracy: 32\%), and Llama shows the highest variance (CV: 47.0\%) with lowest accuracy (4\%). However, within a model, consistency can amplify both correct and incorrect interpretations. Our analysis reveals a critical nuance: consistency amplifies outcomes rather than guaranteeing correctness. 71\% of Claude's failures stem from "consistent wrong interpretation": making the same incorrect assumption across all runs. Interestingly, GPT-5 achieves similar early strategic agreement as Claude (diverging at step 3.4 vs.\ 3.2) but exhibits 2.1times higher variance, suggesting that divergence timing alone does not determine consistency. These findings suggest that for production deployment, interpretation accuracy matters more than execution consistency, with implications for agent evaluation and training.

Agentic retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical decision support. These systems iteratively retrieve curated domain knowledge and synthesize it into structured reports before answer selection. Although such pipelines can improve performance, their impact on reliability under model variability remains unclear. In real-world deployment, heterogeneous models may align, diverge, or synchronize errors in ways not captured by accuracy. We evaluated 34 LLMs on 169 expert-curated publicly available radiology questions, comparing zero-shot inference with a radiology-specific multi-step agentic retrieval condition in which all models received identical structured evidence reports derived from curated radiology knowledge. Agentic inference reduced inter-model decision dispersion (median entropy 0.48 vs. 0.13) and increased robustness of correctness across models (mean 0.74 vs. 0.81). Majority consensus also increased overall (P<0.001). Consensus strength and robust correctness remained correlated under both strategies (ho=0.88 for zero-shot; ho=0.87 for agentic), although high agreement did not guarantee correctness. Response verbosity showed no meaningful association with correctness. Among 572 incorrect outputs, 72% were associated with moderate or high clinically assessed severity, although inter-rater agreement was low (appa=0.02). Agentic retrieval therefore was associated with more concentrated decision distributions, stronger consensus, and higher cross-model robustness of correctness. These findings suggest that evaluating agentic systems through accuracy or agreement alone may not always be sufficient, and that complementary analyses of stability, cross-model robustness, and potential clinical impact are needed to characterize reliability under model variability.

Instruction-tuned large language models (LLMs) excel at many tasks, and will even provide explanations for their behavior. Since these models are directly accessible to the public, there is a risk that convincing and wrong explanations can lead to unsupported confidence in LLMs. Therefore, interpretability-faithfulness of self-explanations is an important consideration for AI Safety. Assessing the interpretability-faithfulness of these explanations, termed self-explanations, is challenging as the models are too complex for humans to annotate what is a correct explanation. To address this, we propose employing self-consistency checks as a measure of faithfulness. For example, if an LLM says a set of words is important for making a prediction, then it should not be able to make the same prediction without these words. While self-consistency checks are a common approach to faithfulness, they have not previously been applied to LLM's self-explanations. We apply self-consistency checks to three types of self-explanations: counterfactuals, importance measures, and redactions. Our work demonstrate that faithfulness is both task and model dependent, e.g., for sentiment classification, counterfactual explanations are more faithful for Llama2, importance measures for Mistral, and redaction for Falcon 40B. Finally, our findings are robust to prompt-variations.

Misinformation in healthcare, from vaccine hesitancy to unproven treatments, poses risks to public health and trust in medical systems. While machine learning and natural language processing have advanced automated fact-checking, validating biomedical claims remains uniquely challenging due to complex terminology, the need for domain expertise, and the critical importance of grounding in scientific evidence. We introduce CER (Combining Evidence and Reasoning), a novel framework for biomedical fact-checking that integrates scientific evidence retrieval, reasoning via large language models, and supervised veracity prediction. By integrating the text-generation capabilities of large language models with advanced retrieval techniques for high-quality biomedical scientific evidence, CER effectively mitigates the risk of hallucinations, ensuring that generated outputs are grounded in verifiable, evidence-based sources. Evaluations on expert-annotated datasets (HealthFC, BioASQ-7b, SciFact) demonstrate state-of-the-art performance and promising cross-dataset generalization. Code and data are released for transparency and reproducibility: https://github.com/PRAISELab-PicusLab/CER

Clinical evidence, derived from rigorous research and data analysis, provides healthcare professionals with reliable scientific foundations for informed decision-making. Integrating clinical evidence into real-time practice is challenging due to the enormous workload, complex professional processes, and time constraints. This highlights the need for tools that automate evidence synthesis to support more efficient and accurate decision making in clinical settings. This study introduces Quicker, an evidence-based clinical decision support system powered by large language models (LLMs), designed to automate evidence synthesis and generate clinical recommendations modeled after standard clinical guideline development processes. Quicker implements a fully automated chain that covers all phases, from questions to clinical recommendations, and further enables customized decision-making through integrated tools and interactive user interfaces. To evaluate Quicker's capabilities, we developed the Q2CRBench-3 benchmark dataset, based on clinical guideline development records for three different diseases. Experimental results highlighted Quicker's strong performance, with fine-grained question decomposition tailored to user preferences, retrieval sensitivities comparable to human experts, and literature screening performance approaching comprehensive inclusion of relevant studies. In addition, Quicker-assisted evidence assessment effectively supported human reviewers, while Quicker's recommendations were more comprehensive and logically coherent than those of clinicians. In system-level testing, collaboration between a single reviewer and Quicker reduced the time required for recommendation development to 20-40 minutes. In general, our findings affirm the potential of Quicker to help physicians make quicker and more reliable evidence-based clinical decisions.

The rise of large language models (LLMs) has significantly influenced the quality of information in decision-making systems, leading to the prevalence of AI-generated content and challenges in detecting misinformation and managing conflicting information, or "inter-evidence conflicts." This study introduces a method for generating diverse, validated evidence conflicts to simulate real-world misinformation scenarios. We evaluate conflict detection methods, including Natural Language Inference (NLI) models, factual consistency (FC) models, and LLMs, on these conflicts (RQ1) and analyze LLMs' conflict resolution behaviors (RQ2). Our key findings include: (1) NLI and LLM models exhibit high precision in detecting answer conflicts, though weaker models suffer from low recall; (2) FC models struggle with lexically similar answer conflicts, while NLI and LLM models handle these better; and (3) stronger models like GPT-4 show robust performance, especially with nuanced conflicts. For conflict resolution, LLMs often favor one piece of conflicting evidence without justification and rely on internal knowledge if they have prior beliefs.

Misinformation in healthcare, from vaccine hesitancy to unproven treatments, poses risks to public health and trust in medical systems. While machine learning and natural language processing have advanced automated fact-checking, validating biomedical claims remains uniquely challenging due to complex terminology, the need for domain expertise, and the critical importance of grounding in scientific evidence. We introduce CER (Combining Evidence and Reasoning), a novel framework for biomedical fact-checking that integrates scientific evidence retrieval, reasoning via large language models, and supervised veracity prediction. By integrating the text-generation capabilities of large language models with advanced retrieval techniques for high-quality biomedical scientific evidence, CER effectively mitigates the risk of hallucinations, ensuring that generated outputs are grounded in verifiable, evidence-based sources. Evaluations on expert-annotated datasets (HealthFC, BioASQ-7b, SciFact) demonstrate state-of-the-art performance and promising cross-dataset generalization. Code and data are released for transparency and reproducibility: https: //github.com/PRAISELab-PicusLab/CER.

Retrieval-augmented generation (RAG) promises grounded question answering, yet domain settings with multiple heterogeneous knowledge bases (KBs) remain challenging. In Chinese Tibetan medicine, encyclopedia entries are often dense and easy to match, which can dominate retrieval even when classics or clinical papers provide more authoritative evidence. We study a practical setting with three KBs (encyclopedia, classics, and clinical papers) and a 500-query benchmark (cutoff K{=}5) covering both single-KB and cross-KB questions. We propose two complementary methods to improve traceability, reduce hallucinations, and enable cross-KB verification. First, DAKS performs KB routing and budgeted retrieval to mitigate density-driven bias and to prioritize authoritative sources when appropriate. Second, we use an alignment graph to guide evidence fusion and coverage-aware packing, improving cross-KB evidence coverage without relying on naive concatenation. All answers are generated by a lightweight generator, openPangu-Embedded-7B. Experiments show consistent gains in routing quality and cross-KB evidence coverage, with the full system achieving the best CrossEv@5 while maintaining strong faithfulness and citation correctness.

Retrieval-augmented language models are being increasingly tasked with subjective, contentious, and conflicting queries such as "is aspartame linked to cancer". To resolve these ambiguous queries, one must search through a large range of websites and consider "which, if any, of this evidence do I find convincing?". In this work, we study how LLMs answer this question. In particular, we construct ConflictingQA, a dataset that pairs controversial queries with a series of real-world evidence documents that contain different facts (e.g., quantitative results), argument styles (e.g., appeals to authority), and answers (Yes or No). We use this dataset to perform sensitivity and counterfactual analyses to explore which text features most affect LLM predictions. Overall, we find that current models rely heavily on the relevance of a website to the query, while largely ignoring stylistic features that humans find important such as whether a text contains scientific references or is written with a neutral tone. Taken together, these results highlight the importance of RAG corpus quality (e.g., the need to filter misinformation), and possibly even a shift in how LLMs are trained to better align with human judgements.

Large language models (LLMs) and agentic systems have shown promise for clinical decision support, but existing works largely assume that evidence has already been curated and handed to the model. Real-world clinical workflows instead require agents to actively seek, iteratively plan, and synthesize multimodal evidence from heterogeneous sources. In this paper, we introduce ClinSeekAgent, an automated agentic framework for dynamic multimodal evidence seeking that shifts the paradigm from passive evidence consumption to active evidence acquisition. Given only a clinical query and access to raw data sources, ClinSeekAgent gathers evidence by querying medical knowledge bases, navigating raw EHRs, and invoking medical imaging tools; refines its hypotheses as new information emerges; and integrates the collected evidence into grounded clinical decisions. ClinSeekAgent serves both as an inference-time agent for frontier LLMs and as a training-time pipeline for distilling high-quality agent trajectories into compact open-source models. To validate its inference-time effectiveness, we construct ClinSeek-Bench, which pairs Curated Input reasoning from fixed pre-selected evidence with Automated Evidence-Seeking over raw clinical data. On text-only EHR tasks, ClinSeekAgent improves Claude Opus 4.6 from 60.0 to 63.2 overall F1 and MiniMax M2.5 from 43.1 to 47.3, with positive risk-prediction gains in 7 out of 9 evaluated host models. On multimodal tasks, ClinSeekAgent improves Claude Opus 4.6 from 47.5 to 62.6 (+15.1); all evaluated models improve across the three CXR-related task groups. We further validate ClinSeekAgent as a training pipeline by distilling agentic evidence-seeking trajectories into ClinSeek-35B-A3B, which achieves 34.0 average F1 on existing AgentEHR-Bench, improving over its Qwen3.5-35B-A3B baseline by +11.9 points and approaching Claude Opus 4.6.

Chain-of-thought (CoT) offers a potential boon for AI safety as it allows monitoring a model's CoT to try to understand its intentions and reasoning processes. However, the effectiveness of such monitoring hinges on CoTs faithfully representing models' actual reasoning processes. We evaluate CoT faithfulness of state-of-the-art reasoning models across 6 reasoning hints presented in the prompts and find: (1) for most settings and models tested, CoTs reveal their usage of hints in at least 1% of examples where they use the hint, but the reveal rate is often below 20%, (2) outcome-based reinforcement learning initially improves faithfulness but plateaus without saturating, and (3) when reinforcement learning increases how frequently hints are used (reward hacking), the propensity to verbalize them does not increase, even without training against a CoT monitor. These results suggest that CoT monitoring is a promising way of noticing undesired behaviors during training and evaluations, but that it is not sufficient to rule them out. They also suggest that in settings like ours where CoT reasoning is not necessary, test-time monitoring of CoTs is unlikely to reliably catch rare and catastrophic unexpected behaviors.

Medication reconciliation at clinical handoffs is a high-stakes, error-prone process. Large language models are increasingly proposed to assist with this task using FHIR-structured patient records, but a fundamental and largely unstudied variable is how the FHIR data is serialised before being passed to the model. We present the first systematic comparison of four FHIR serialisation strategies (Raw JSON, Markdown Table, Clinical Narrative, and Chronological Timeline) across five open-weight models (Phi-3.5-mini, Mistral-7B, BioMistral-7B, Llama-3.1-8B, Llama-3.3-70B) on a controlled benchmark of 200 synthetic patients, totalling 4,000 inference runs. We find that serialisation strategy has a large, statistically significant effect on performance for models up to 8B parameters: Clinical Narrative outperforms Raw JSON by up to 19 F1 points for Mistral-7B (r = 0.617, p < 10^{-10}). This advantage reverses at 70B, where Raw JSON achieves the best mean F1 of 0.9956. In all 20 model and strategy combinations, mean precision exceeds mean recall: omission is the dominant failure mode, with models more often missing an active medication than fabricating one, which changes how clinical safety auditing priorities should be set. Smaller models plateau at roughly 7-10 concurrent active medications, leaving polypharmacy patients, the patients most at risk from reconciliation errors, systematically underserved. BioMistral-7B, a domain-pretrained model without instruction tuning, produces zero usable output in all conditions, showing that domain pretraining alone is not sufficient for structured extraction. These results offer practical, evidence-based format recommendations for clinical LLM deployment: Clinical Narrative for models up to 8B, Raw JSON for 70B and above. The complete pipeline is reproducible on open-source tools running on an AWS g6e.xlarge instance (NVIDIA L40S, 48 GB VRAM).

Large Reasoning Models (LRMs) have significantly enhanced their capabilities in complex problem-solving by introducing a thinking draft that enables multi-path Chain-of-Thought explorations before producing final answers. Ensuring the faithfulness of these intermediate reasoning processes is crucial for reliable monitoring, interpretation, and effective control. In this paper, we propose a systematic counterfactual intervention framework to rigorously evaluate thinking draft faithfulness. Our approach focuses on two complementary dimensions: (1) Intra-Draft Faithfulness, which assesses whether individual reasoning steps causally influence subsequent steps and the final draft conclusion through counterfactual step insertions; and (2) Draft-to-Answer Faithfulness, which evaluates whether final answers are logically consistent with and dependent on the thinking draft, by perturbing the draft's concluding logic. We conduct extensive experiments across six state-of-the-art LRMs. Our findings show that current LRMs demonstrate selective faithfulness to intermediate reasoning steps and frequently fail to faithfully align with the draft conclusions. These results underscore the need for more faithful and interpretable reasoning in advanced LRMs.

Misinformation - false or misleading information - is considered a significant societal concern due to its associated "misinformation effects," such as political polarization, erosion of trust in institutions, problematic behavior, and public health challenges. However, the prevailing concept is misaligned with what is studied. While misinformation focuses on instances of information about factual matters, the broad spectrum of effects often manifests at a societal level and is shaped by a wide range of interdependent factors such as identity, values, opinions, epistemologies, and disagreements. Unsurprisingly, misinformation effects can occur without the prevalence of misinformation, and misinformation does not necessarily increase the effects studied. Here, we propose using disagreement - conflicting attitudes and beliefs between individuals and communities - as a way to study misinformation effects because it addresses the identified conceptual limitations of misinformation. Furthermore, unlike misinformation, disagreement does not require researchers to determine whether a given information is false or misleading. Thus, it can be studied and, more importantly, measured without the need to make a normative judgment about a given information, even when the specific topic is entirely removed, as we show in a longitudinal disagreement measurement. We demonstrate that disagreement, as a holistic concept, provides better explanations for the occurrence of misinformation effects, enhances precision in developing appropriate interventions, and offers a promising approach for evaluating them through quantification. Finally, we show how disagreement addresses current misinformation research questions and conclude with recommendations for research practice.

Recent advances in long chain-of-thought (CoT) reasoning have largely prioritized answer accuracy and token efficiency, while overlooking aspects critical to trustworthiness. We argue that usable reasoning systems must be trustworthy, characterized by three properties: interpretability, faithfulness, and reliability. To this end, we propose ReFIne, a new training framework that integrates supervised fine-tuning with GRPO to encourage models to: (i) improve interpretability by producing structured, tag-based traces with high-level planning that are easier for humans to follow; (ii) enhance faithfulness by explicitly disclosing the decisive information guiding each solution, with consistent cross-section references; and (iii) promote reliability by providing self-assessments of both the derivation's soundness and the confidence of the final answer. We apply ReFIne to the Qwen3 models at multiple scales (1.7B/4B/8B) and evaluate across mathematical benchmarks of varying difficulty. Our experimental results show that ReFIne models generate clearer and better-structured reasoning traces (interpretability +44.0%), more faithfully expose their underlying decision process (faithfulness +18.8%), and offer informative confidence estimates (reliability +42.4%). These findings highlight an overlooked but important direction: reasoning models should be optimized not only for accuracy, but also for broader dimensions of trustworthiness. Our code is available at: https://github.com/Trustworthy-ML-Lab/Training_Trustworthy_LRM_with_Refine

LLM-judged benchmarks are increasingly used to evaluate complex model behaviors, yet their design introduces failure modes absent in conventional ground-truth based benchmarks. We argue that without tight objectives and verifiable constructions, benchmark rankings can produce high-confidence rankings that are in fact largely noise. We introduce two mechanisms to diagnose these issues. Schematic adherence quantifies how much of a judge's overall verdict is explained by the explicit evaluation schema, revealing unexplained variance when judges deviate from their own rubric. Psychometric validity aggregates internal consistency and discriminant validity signals to quantify irreducible uncertainty in any benchmarking run. Applying these tools to Arena-Hard Auto, we find severe schema incoherence and factor collapse across popular judges: for example, unexplained variance exceeding 90 percent for DeepSeek-R1-32B and factor correlations above 0.93 for most criteria. We also show that the ELO-style aggregation used by Arena-Hard Auto collapses and masks genuine ranking uncertainty. Our results highlight design failures that undermine validity and offer actionable principles for building better-scoped, reliability-aware LLM-judged benchmarks. We release our code at https://anonymous.4open.science/r/judgment-to-noise-947D/README.md

Large language models that use retrieval augmented generation have the potential to unlock valuable knowledge for researchers, policymakers, and the public by making long and technical climate-related documents more accessible. While this approach can help alleviate factual hallucinations by relying on retrieved passages as additional context, its effectiveness depends on whether the model's output remains faithful to these passages. To address this, we explore the automatic assessment of faithfulness of different models in this setting. We then focus on ClimateGPT, a large language model specialised in climate science, to examine which factors in its instruction fine-tuning impact the model's faithfulness. By excluding unfaithful subsets of the model's training data, we develop ClimateGPT Faithful+, which achieves an improvement in faithfulness from 30% to 57% in supported atomic claims according to our automatic metric.

In ad text generation (ATG), desirable ad text is both faithful and informative. That is, it should be faithful to the input document, while at the same time containing important information that appeals to potential customers. The existing evaluation data, CAMERA (arXiv:2309.12030), is suitable for evaluating informativeness, as it consists of reference ad texts created by ad creators. However, these references often include information unfaithful to the input, which is a notable obstacle in promoting ATG research. In this study, we collaborate with in-house ad creators to refine the CAMERA references and develop an alternative ATG evaluation dataset called FaithCAMERA, in which the faithfulness of references is guaranteed. Using FaithCAMERA, we can evaluate how well existing methods for improving faithfulness can generate informative ad text while maintaining faithfulness. Our experiments show that removing training data that contains unfaithful entities improves the faithfulness and informativeness at the entity level, but decreases both at the sentence level. This result suggests that for future ATG research, it is essential not only to scale the training data but also to ensure their faithfulness. Our dataset will be publicly available.

Randomized controlled trials often do not represent the populations where decisions are made, and covariate shift across studies can invalidate standard IPD meta-analysis and transport estimators. We propose a placebo-anchored transport framework that treats source-trial outcomes as abundant proxy signals and target-trial placebo outcomes as scarce, high-fidelity gold labels to calibrate baseline risk. A low-complexity (sparse) correction anchors proxy outcome models to the target population, and the anchored models are embedded in a cross-fitted doubly robust learner, yielding a Neyman-orthogonal, target-site doubly robust estimator for patient-level heterogeneous treatment effects when target treated outcomes are available. We distinguish two regimes: in connected targets (with a treated arm), the method yields target-identified effect estimates; in disconnected targets (placebo-only), it reduces to a principled screen--then--transport procedure under explicit working-model transport assumptions. Experiments on synthetic data and a semi-synthetic IHDP benchmark evaluate pointwise CATE accuracy, ATE error, ranking quality for targeting, decision-theoretic policy regret, and calibration. Across connected settings, the proposed method is best or near-best and improves substantially over proxy-only, target-only, and transport baselines at small target sample sizes; in disconnected settings, it retains strong ranking performance for targeting while pointwise accuracy depends on the strength of the working transport condition.

This article presents a pipeline for automated fact-checking leveraging publicly available Language Models and data. The objective is to assess the accuracy of textual claims using evidence from a ground-truth evidence corpus. The pipeline consists of two main modules -- the evidence retrieval and the claim veracity evaluation. Our primary focus is on the ease of deployment in various languages that remain unexplored in the field of automated fact-checking. Unlike most similar pipelines, which work with evidence sentences, our pipeline processes data on a paragraph level, simplifying the overall architecture and data requirements. Given the high cost of annotating language-specific fact-checking training data, our solution builds on the Question Answering for Claim Generation (QACG) method, which we adapt and use to generate the data for all models of the pipeline. Our strategy enables the introduction of new languages through machine translation of only two fixed datasets of moderate size. Subsequently, any number of training samples can be generated based on an evidence corpus in the target language. We provide open access to all data and fine-tuned models for Czech, English, Polish, and Slovak pipelines, as well as to our codebase that may be used to reproduce the results.We comprehensively evaluate the pipelines for all four languages, including human annotations and per-sample difficulty assessment using Pointwise V-information. The presented experiments are based on full Wikipedia snapshots to promote reproducibility. To facilitate implementation and user interaction, we develop the FactSearch application featuring the proposed pipeline and the preliminary feedback on its performance.

While there are numerous benchmarks comparing the performance of modern language models (LMs), end-task evaluations often conflate notions of *factual accuracy* ("truth") and *reasoning ability* ("rationality", or "honesty" in the sense of correctly reporting implications of beliefs). Our goal is a dataset that clearly distinguishes these two notions. Our approach is to leverage and extend a collection of human-annotated *entailment trees*, engineered to express both good and bad chains of reasoning, and using a mixture of true and false facts, in particular including counterfactual examples, to avoid belief bias (also known as the "content effect"). The resulting dataset, called BaRDa, contains 3000 entailments (1787 valid, 1213 invalid), using 6681 true and 2319 false statements. Testing on four GPT-series models, GPT3(curie)/GPT3(davinici)/3.5/4, we find factual accuracy (truth) scores of 74.1/80.6/82.6/87.1 and reasoning accuracy scores of 63.1/78.0/71.8/79.2. This shows the clear progression of models towards improved factual accuracy and entailment reasoning, and the dataset provides a new benchmark that more cleanly separates and quantifies these two notions.

Summaries of medical text shall be faithful by being consistent and factual with source inputs, which is an important but understudied topic for safety and efficiency in healthcare. In this paper, we investigate and improve faithfulness in summarization on a broad range of medical summarization tasks. Our investigation reveals that current summarization models often produce unfaithful outputs for medical input text. We then introduce FaMeSumm, a framework to improve faithfulness by fine-tuning pre-trained language models based on medical knowledge. FaMeSumm performs contrastive learning on designed sets of faithful and unfaithful summaries, and it incorporates medical terms and their contexts to encourage faithful generation of medical terms. We conduct comprehensive experiments on three datasets in two languages: health question and radiology report summarization datasets in English, and a patient-doctor dialogue dataset in Chinese. Results demonstrate that FaMeSumm is flexible and effective by delivering consistent improvements over mainstream language models such as BART, T5, mT5, and PEGASUS, yielding state-of-the-art performances on metrics for faithfulness and general quality. Human evaluation by doctors also shows that FaMeSumm generates more faithful outputs. Our code is available at https://github.com/psunlpgroup/FaMeSumm .

While Reinforcement Learning (RL) has advanced LLM reasoning, applying it to long-context scenarios is hindered by sparsity of outcome rewards. This limitation fails to penalize ungrounded "lucky guesses," leaving the critical process of needle-in-a-haystack evidence retrieval largely unsupervised. To address this, we propose EAPO (Evidence-Augmented Policy Optimization). We first establish the Evidence-Augmented Reasoning paradigm, validating via Tree-Structured Evidence Sampling that precise evidence extraction is the decisive bottleneck for long-context reasoning. Guided by this insight, EAPO introduces a specialized RL algorithm where a reward model computes a Group-Relative Evidence Reward, providing dense process supervision to explicitly improve evidence quality. To sustain accurate supervision throughout training, we further incorporate an Adaptive Reward-Policy Co-Evolution mechanism. This mechanism iteratively refines the reward model using outcome-consistent rollouts, sharpening its discriminative capability to ensure precise process guidance. Comprehensive evaluations across eight benchmarks demonstrate that EAPO significantly enhances long-context reasoning performance compared to SOTA baselines.

Reliable pattern recognition systems should exhibit consistent behavior across similar inputs, and their explanations should remain stable. However, most Explainable AI evaluations remain instance centric and do not explicitly quantify whether attribution patterns are consistent across samples that share the same class or represent small variations of the same input. In this work, we propose a novel metric aimed at assessing the consistency of model explanations, ensuring that models consistently reflect the intended objectives and consistency under label-preserving perturbations. We implement this metric using a pre-trained BERT model on the SST-2 sentiment analysis dataset, with additional robustness tests on RoBERTa, DistilBERT, and IMDB, applying SHAP to compute feature importance for various test samples. The proposed metric quantifies the cosine similarity of SHAP values for inputs with the same label, aiming to detect inconsistent behaviors, such as biased reliance on certain features or failure to maintain consistent reasoning for similar predictions. Through a series of experiments, we evaluate the ability of this metric to identify misaligned predictions and inconsistencies in model explanations. These experiments are compared against standard fidelity metrics to assess whether the new metric can effectively identify when a model's behavior deviates from its intended objectives. The proposed framework provides a deeper understanding of model behavior by enabling more robust verification of rationale stability, which is critical for building trustworthy AI systems. By quantifying whether models rely on consistent attribution patterns for similar inputs, the proposed approach supports more robust evaluation of model behavior in practical pattern recognition pipelines. Our code is publicly available at https://github.com/anmspro/ESS-XAI-Stability.

Laboratory accidents pose significant risks to human life and property, underscoring the importance of robust safety protocols. Despite advancements in safety training, laboratory personnel may still unknowingly engage in unsafe practices. With the increasing reliance on large language models (LLMs) for guidance in various fields, including laboratory settings, there is a growing concern about their reliability in critical safety-related decision-making. Unlike trained human researchers, LLMs lack formal lab safety education, raising questions about their ability to provide safe and accurate guidance. Existing research on LLM trustworthiness primarily focuses on issues such as ethical compliance, truthfulness, and fairness but fails to fully cover safety-critical real-world applications, like lab safety. To address this gap, we propose the Laboratory Safety Benchmark (LabSafety Bench), a comprehensive evaluation framework based on a new taxonomy aligned with Occupational Safety and Health Administration (OSHA) protocols. This benchmark includes 765 multiple-choice questions verified by human experts, assessing LLMs and vision language models (VLMs) performance in lab safety contexts. Our evaluations demonstrate that while GPT-4o outperforms human participants, it is still prone to critical errors, highlighting the risks of relying on LLMs in safety-critical environments. Our findings emphasize the need for specialized benchmarks to accurately assess the trustworthiness of LLMs in real-world safety applications.

We propose CRAVE (Cluster-based Retrieval Augmented Verification with Explanation); a novel framework that integrates retrieval-augmented Large Language Models (LLMs) with clustering techniques to address fact-checking challenges on social media. CRAVE automatically retrieves multimodal evidence from diverse, often contradictory, sources. Evidence is clustered into coherent narratives, and evaluated via an LLM-based judge to deliver fact-checking verdicts explained by evidence summaries. By synthesizing evidence from both text and image modalities and incorporating agent-based refinement, CRAVE ensures consistency and diversity in evidence representation. Comprehensive experiments demonstrate CRAVE's efficacy in retrieval precision, clustering quality, and judgment accuracy, showcasing its potential as a robust decision-support tool for fact-checkers.

Recent research in the field of reflexive metrics have studied the emergence and consequences of evaluation gaps in science. The concept of evaluation gaps captures potential discrepancies between what researchers value about their research, in particular research quality, and what metrics measure. As a result, scientists may experience anomie and adopt innovative ways to cope. These often value quantity over quality and may even compromise research integrity. A consequence of such gaps may therefore be research misconduct and a decrease in research quality. In the language of rational choice theory, an evaluation gap persists if motivational factors arising out of the internal component of an actors situation are incongruent with those arising out of the external components. The aim of this research is therefore to study and compare autonomous and controlled motivations to become an astronomer, to do research in astronomy and to publish scientific papers. Moreover, we study how these different motivational factors affect publication pressure, the experience of organisational justice and the observation of research misconduct. In summary, we find evidence for an evaluation gap and that controlled motivational factors arising from evaluation procedures based on publication record drives up publication pressure, which, in turn, was found to increase the likelihood of perceived frequency of misbehaviour.

Large Language Models (LLMs) are extensively used today across various sectors, including academia, research, business, and finance, for tasks such as text generation, summarization, and translation. Despite their widespread adoption, these models often produce incorrect and misleading information, exhibiting a tendency to hallucinate. This behavior can be attributed to several factors, with consistency and reasoning capabilities being significant contributors. LLMs frequently lack the ability to generate explanations and engage in coherent reasoning, leading to inaccurate responses. Moreover, they exhibit inconsistencies in their outputs. This paper aims to evaluate and compare the consistency and reasoning capabilities of both public and proprietary LLMs. The experiments utilize the Boolq dataset as the ground truth, comprising questions, answers, and corresponding explanations. Queries from the dataset are presented as prompts to the LLMs, and the generated responses are evaluated against the ground truth answers. Additionally, explanations are generated to assess the models' reasoning abilities. Consistency is evaluated by repeatedly presenting the same query to the models and observing for variations in their responses. For measuring reasoning capabilities, the generated explanations are compared to the ground truth explanations using metrics such as BERT, BLEU, and F-1 scores. The findings reveal that proprietary models generally outperform public models in terms of both consistency and reasoning capabilities. However, even when presented with basic general knowledge questions, none of the models achieved a score of 90\% in both consistency and reasoning. This study underscores the direct correlation between consistency and reasoning abilities in LLMs and highlights the inherent reasoning challenges present in current language models.

Assessing whether an article supports an assertion is essential for hallucination detection and claim verification. While large language models (LLMs) have the potential to automate this task, achieving strong performance requires frontier models such as GPT-5 that are prohibitively expensive to deploy at scale. To efficiently perform biomedical evidence attribution, we present Med-V1, a family of small language models with only three billion parameters. Trained on high-quality synthetic data newly developed in this study, Med-V1 substantially outperforms (+27.0% to +71.3%) its base models on five biomedical benchmarks unified into a verification format. Despite its smaller size, Med-V1 performs comparably to frontier LLMs such as GPT-5, along with high-quality explanations for its predictions. We use Med-V1 to conduct a first-of-its-kind use case study that quantifies hallucinations in LLM-generated answers under different citation instructions. Results show that the format instruction strongly affects citation validity and hallucination, with GPT-5 generating more claims but exhibiting hallucination rates similar to GPT-4o. Additionally, we present a second use case showing that Med-V1 can automatically identify high-stakes evidence misattributions in clinical practice guidelines, revealing potentially negative public health impacts that are otherwise challenging to identify at scale. Overall, Med-V1 provides an efficient and accurate lightweight alternative to frontier LLMs for practical and real-world applications in biomedical evidence attribution and verification tasks. Med-V1 is available at https://github.com/ncbi-nlp/Med-V1.

This study investigates GPT-4's assessment of its performance in healthcare applications. A simple prompting technique was used to prompt the LLM with questions taken from the United States Medical Licensing Examination (USMLE) questionnaire and it was tasked to evaluate its confidence score before posing the question and after asking the question. The questionnaire was categorized into two groups-questions with feedback (WF) and questions with no feedback(NF) post-question. The model was asked to provide absolute and relative confidence scores before and after each question. The experimental findings were analyzed using statistical tools to study the variability of confidence in WF and NF groups. Additionally, a sequential analysis was conducted to observe the performance variation for the WF and NF groups. Results indicate that feedback influences relative confidence but doesn't consistently increase or decrease it. Understanding the performance of LLM is paramount in exploring its utility in sensitive areas like healthcare. This study contributes to the ongoing discourse on the reliability of AI, particularly of LLMs like GPT-4, within healthcare, offering insights into how feedback mechanisms might be optimized to enhance AI-assisted medical education and decision support.

Retrieval-enhanced methods have become a primary approach in fact verification (FV); it requires reasoning over multiple retrieved pieces of evidence to verify the integrity of a claim. To retrieve evidence, existing work often employs off-the-shelf retrieval models whose design is based on the probability ranking principle. We argue that, rather than relevance, for FV we need to focus on the utility that a claim verifier derives from the retrieved evidence. We introduce the feedback-based evidence retriever(FER) that optimizes the evidence retrieval process by incorporating feedback from the claim verifier. As a feedback signal we use the divergence in utility between how effectively the verifier utilizes the retrieved evidence and the ground-truth evidence to produce the final claim label. Empirical studies demonstrate the superiority of FER over prevailing baselines.

Large Language Models (LLMs) have great potential in the field of health care, yet they face great challenges in adapting to rapidly evolving medical knowledge. This can lead to outdated or contradictory treatment suggestions. This study investigated how LLMs respond to evolving clinical guidelines, focusing on concept drift and internal inconsistencies. We developed the DriftMedQA benchmark to simulate guideline evolution and assessed the temporal reliability of various LLMs. Our evaluation of seven state-of-the-art models across 4,290 scenarios demonstrated difficulties in rejecting outdated recommendations and frequently endorsing conflicting guidance. Additionally, we explored two mitigation strategies: Retrieval-Augmented Generation and preference fine-tuning via Direct Preference Optimization. While each method improved model performance, their combination led to the most consistent and reliable results. These findings underscore the need to improve LLM robustness to temporal shifts to ensure more dependable applications in clinical practice.

We present a complete theoretical characterization of Latent Posterior Factors (LPF), a principled framework for aggregating multiple heterogeneous evidence items in probabilistic prediction tasks. Multi-evidence reasoning arises pervasively in high-stakes domains including healthcare diagnosis, financial risk assessment, legal case analysis, and regulatory compliance, yet existing approaches either lack formal guarantees or fail to handle multi-evidence scenarios architecturally. LPF encodes each evidence item into a Gaussian latent posterior via a variational autoencoder, converting posteriors to soft factors through Monte Carlo marginalization, and aggregating factors via exact Sum-Product Network inference (LPF-SPN) or a learned neural aggregator (LPF-Learned). We prove seven formal guarantees spanning the key desiderata for trustworthy AI: Calibration Preservation (ECE <= epsilon + C/sqrt(K_eff)); Monte Carlo Error decaying as O(1/sqrt(M)); a non-vacuous PAC-Bayes bound with train-test gap of 0.0085 at N=4200; operation within 1.12x of the information-theoretic lower bound; graceful degradation as O(epsilon*delta*sqrt(K)) under corruption, maintaining 88% performance with half of evidence adversarially replaced; O(1/sqrt(K)) calibration decay with R^2=0.849; and exact epistemic-aleatoric uncertainty decomposition with error below 0.002%. All theorems are empirically validated on controlled datasets spanning up to 4,200 training examples. Our theoretical framework establishes LPF as a foundation for trustworthy multi-evidence AI in safety-critical applications.

Grounded text generation systems often generate text that contains factual inconsistencies, hindering their real-world applicability. Automatic factual consistency evaluation may help alleviate this limitation by accelerating evaluation cycles, filtering inconsistent outputs and augmenting training data. While attracting increasing attention, such evaluation metrics are usually developed and evaluated in silo for a single task or dataset, slowing their adoption. Moreover, previous meta-evaluation protocols focused on system-level correlations with human annotations, which leave the example-level accuracy of such metrics unclear. In this work, we introduce TRUE: a comprehensive survey and assessment of factual consistency metrics on a standardized collection of existing texts from diverse tasks, manually annotated for factual consistency. Our standardization enables an example-level meta-evaluation protocol that is more actionable and interpretable than previously reported correlations, yielding clearer quality measures. Across diverse state-of-the-art metrics and 11 datasets we find that large-scale NLI and question generation-and-answering-based approaches achieve strong and complementary results. We recommend those methods as a starting point for model and metric developers, and hope TRUE will foster progress towards even better evaluation methods.

Background: Agent skills are increasingly deployed as modular, reusable capability units in AI agent systems. Medical research agent skills require safeguards beyond general-purpose evaluation, including scientific integrity, methodological validity, reproducibility, and boundary safety. This study developed and preliminarily evaluated a domain-specific audit framework for medical research agent skills, with a focus on reliability against expert review. Methods: We developed MedSkillAudit (skill-auditor@1.0), a layered framework assessing skill release readiness before deployment. We evaluated 75 skills across five medical research categories (15 per category). Two experts independently assigned a quality score (0-100), an ordinal release disposition (Production Ready / Limited Release / Beta Only / Reject), and a high-risk failure flag. System-expert agreement was quantified using ICC(2,1) and linearly weighted Cohen's kappa, benchmarked against the human inter-rater baseline. Results: The mean consensus quality score was 72.4 (SD = 13.0); 57.3% of skills fell below the Limited Release threshold. MedSkillAudit achieved ICC(2,1) = 0.449 (95% CI: 0.250-0.610), exceeding the human inter-rater ICC of 0.300. System-consensus score divergence (SD = 9.5) was smaller than inter-expert divergence (SD = 12.4), with no directional bias (Wilcoxon p = 0.613). Protocol Design showed the strongest category-level agreement (ICC = 0.551); Academic Writing showed a negative ICC (-0.567), reflecting a structural rubric-expert mismatch. Conclusions: Domain-specific pre-deployment audit may provide a practical foundation for governing medical research agent skills, complementing general-purpose quality checks with structured audit workflows tailored to scientific use cases.

Large Language Models (LLMs) augmented with retrieval mechanisms have demonstrated significant potential in fact-checking tasks by integrating external knowledge. However, their reliability decreases when confronted with conflicting evidence from sources of varying credibility. This paper presents the first systematic evaluation of Retrieval-Augmented Generation (RAG) models for fact-checking in the presence of conflicting evidence. To support this study, we introduce CONFACT (Conflicting Evidence for Fact-Checking) (Dataset available at https://github.com/zoeyyes/CONFACT), a novel dataset comprising questions paired with conflicting information from various sources. Extensive experiments reveal critical vulnerabilities in state-of-the-art RAG methods, particularly in resolving conflicts stemming from differences in media source credibility. To address these challenges, we investigate strategies to integrate media background information into both the retrieval and generation stages. Our results show that effectively incorporating source credibility significantly enhances the ability of RAG models to resolve conflicting evidence and improve fact-checking performance.

A critical component in the trustworthiness of LLMs is reliable uncertainty communication, yet LLMs often use assertive language when conveying false claims, leading to over-reliance and eroded trust. We present the first systematic study of faithful confidence calibration of LLMs, benchmarking models' ability to use linguistic expressions of uncertainty that faithfully reflect their intrinsic uncertainty, across a comprehensive array of models, datasets, and prompting strategies. Our results demonstrate that LLMs largely fail at this task, and that existing interventions are insufficient: standard prompt approaches provide only marginal gains, and existing, factuality-based calibration techniques can even harm faithful calibration. To address this critical gap, we introduce MetaFaith, a novel prompt-based calibration approach inspired by human metacognition. We show that MetaFaith robustly improves faithful calibration across diverse models and task domains, enabling up to 61% improvement in faithfulness and achieving an 83% win rate over original generations as judged by humans.

Recent work on reinforcement learning with verifiable rewards (RLVR) has shown that large language models (LLMs) can be substantially improved using outcome-level verification signals, such as unit tests for code or exact-match checks for mathematics. In parallel, process supervision has long been explored as a way to shape the intermediate reasoning behaviour of LLMs, but existing approaches rely on neural judges to score chain-of-thought steps, leaving them vulnerable to opacity, bias, and reward hacking. To address this gap, we introduce Verifiable Process Reward Models (VPRMs), a reinforcement-learning framework in which intermediate reasoning steps are checked by deterministic, rule-based verifiers. We apply VPRMs to risk-of-bias assessment for medical evidence synthesis, a domain where guideline-defined criteria and rule-based decision paths enable programmatic verification of reasoning traces. Across multiple datasets, we find that VPRMs generate reasoning that adheres closely to domain rules and achieve substantially higher coherence between step-level decisions and final labels. Results show that VPRMs achieve up to 20% higher F1 than state-of-the-art models and 6.5% higher than verifiable outcome rewards, with substantial gains in evidence grounding and logical coherence.

Through reinforcement learning with verifiable rewards (RLVR), large language models have achieved substantial progress in domains with easily verifiable outcomes, such as mathematics and coding. However, when applied to more complex tasks like open-domain question answering, RLVR faces significant challenges due to the difficulty of verifying correctness. The nuanced and ambiguous nature of real-world knowledge makes it difficult to reliably evaluate correctness in these settings, necessitating further abilities that extend beyond mere logical consistency to encompass an understanding and assessment of both external and internal knowledge. Recent work has primarily focused on improving faithfulness, defined as semantic alignment with supporting documents, which can cause models to rely excessively on external sources and diminish their capacity for critical assessment. To address this, we propose the Thinking-supervised Reward Model (TRM), which incorporates sentence-level thinking supervision to endow reward models with critical thinking abilities. Given a query, answer, and supporting documents, TRM first assesses the faithfulness of each answer sentence to the supporting documents, and then applies a reasoning step to evaluate sentence-level correctness. By structuring reward modeling as a sequence of faithfulness, reasoning, and correctness evaluations, TRM encourages models to critically assess and leverage both external and internal knowledge. Experiments on reward signals demonstrate that TRM substantially improves the identification of incorrect sentences, and incorporating TRM into policy optimization leads to significant gains in both answer correctness and usefulness.

This report describes ARIS (Auto-Research-in-sleep), an open-source research harness for autonomous research, including its architecture, assurance mechanisms, and early deployment experience. The performance of agent systems built on LLMs depends on both the model weights and the harness around them, which governs what information to store, retrieve, and present to the model. For long-horizon research workflows, the central failure mode is not a visible breakdown but a plausible unsupported success: a long-running agent can produce claims whose evidential support is incomplete, misreported, or silently inherited from the executor's framing. Therefore, we present ARIS as a research harness that coordinates machine-learning research workflows through cross-model adversarial collaboration as a default configuration: an executor model drives forward progress while a reviewer from a different model family is recommended to critique intermediate artifacts and request revisions. ARIS has three architectural layers. The execution layer provides more than 65 reusable Markdown-defined skills, model integrations via MCP, a persistent research wiki for iterative reuse of prior findings, and deterministic figure generation. The orchestration layer coordinates five end-to-end workflows with adjustable effort settings and configurable routing to reviewer models. The assurance layer includes a three-stage process for checking whether experimental claims are supported by evidence: integrity verification, result-to-claim mapping, and claim auditing that cross-checks manuscript statements against the claim ledger and raw evidence, as well as a five-pass scientific-editing pipeline, mathematical-proof checks, and visual inspection of the rendered PDF. A prototype self-improvement loop records research traces and proposes harness improvements that are adopted only after reviewer approval.

Assessing journal legitimacy during literature reviews, publication venue selection, and citation verification requires consulting information scattered across multiple incompatible data-sets. This paper introduces Aletheia-Probe, an open-source tool that systematically aggregates curated databases and pattern analysis from multiple authoritative sources to provide transparent, confidence-scored journal assessments. The tool explicitly reports which sources were consulted, what each found, and where evidence conflicts. The tool integrates into research workflows through command-line and programmatic interfaces. It reduces manual assessment overhead while explicitly flagging uncertain cases. We present the tool's architecture, core design principles, and practical integration approach. Comprehensive empirical validation will be presented in forthcoming work.

This position paper argues that computer science conferences should require tamper-evident, nonrepudiable attestations of experimental results. We name the underlying problem experiment nonrepudiation: a compliant protocol must bind the numbers in a paper to an actual executed computation in a way the author cannot later alter or deny. The current system relies on self-reported checklists, optional code sharing, and author-controlled logging. None of these mechanisms answer the question a reviewer cannot check: did the code the paper describes produce the numbers the paper reports? We define the problem formally, state the security properties any compliant protocol must satisfy, and describe a threat model that includes attacks current approaches do not prevent. To show that the problem is solvable, we built K-Veritas, a reference implementation in Go that produces signed reports without accessing training data. K-Veritas is a testbed, not a finished answer. We call on conferences and the community to treat nonrepudiation as a first-class requirement and to help build an open, independent standard for it.

Normalised citation counts are routinely used to assess the average impact of research groups or nations. There is controversy over whether confidence intervals for them are theoretically valid or practically useful. In response, this article introduces the concept of a group's underlying research capability to produce impactful research. It then investigates whether confidence intervals could delimit the underlying capability of a group in practice. From 123120 confidence interval comparisons for the average citation impact of the national outputs of ten countries within 36 individual large monodisciplinary journals, moderately fewer than 95% of subsequent indicator values fall within 95% confidence intervals from prior years, with the percentage declining over time. This is consistent with confidence intervals effectively delimiting the research capability of a group, although it does not prove that this is the cause of the results. The results are unaffected by whether internationally collaborative articles are included.

Fact verification is essential for ensuring the reliability of LLM applications. In this study, we evaluate 12 pre-trained LLMs and one specialized fact-verifier, including frontier LLMs and open-weight reasoning LLMs, using a collection of examples from 14 fact-checking benchmarks. We share three findings intended to guide future development of more robust fact verifiers. First, we highlight the importance of addressing annotation errors and ambiguity in datasets, demonstrating that approximately 16\% of ambiguous or incorrectly labeled data substantially influences model rankings. Neglecting this issue may result in misleading conclusions during comparative evaluations, and we suggest using a systematic pipeline utilizing LLM-as-a-judge to help identify these issues at scale. Second, we discover that frontier LLMs with few-shot in-context examples, often overlooked in previous works, achieve top-tier performance. We therefore recommend future studies include comparisons with these simple yet highly effective baselines. Lastly, despite their effectiveness, frontier LLMs incur substantial costs, motivating the development of small, fine-tuned fact verifiers. We show that these small models still have room for improvement, particularly on instances that require complex reasoning. Encouragingly, we demonstrate that augmenting training with synthetic multi-hop reasoning data significantly enhances their capabilities in such instances. We release our code, model, and dataset at https://github.com/just1nseo/verifying-the-verifiers

While Retrieval-Augmented Generation (RAG) mitigates hallucination and knowledge staleness in Large Language Models (LLMs), existing frameworks often falter on complex, multi-hop queries that require synthesizing information from disparate sources. Current advanced RAG methods, employing iterative or adaptive strategies, lack a robust mechanism to systematically identify and fill evidence gaps, often propagating noise or failing to gather a comprehensive context. We introduce FAIR-RAG, a novel agentic framework that transforms the standard RAG pipeline into a dynamic, evidence-driven reasoning process. At its core is an Iterative Refinement Cycle governed by a module we term Structured Evidence Assessment (SEA). The SEA acts as an analytical gating mechanism: it deconstructs the initial query into a checklist of required findings and audits the aggregated evidence to identify confirmed facts and, critically, explicit informational gaps. These gaps provide a precise signal to an Adaptive Query Refinement agent, which generates new, targeted sub-queries to retrieve missing information. This cycle repeats until the evidence is verified as sufficient, ensuring a comprehensive context for a final, strictly faithful generation. We conducted experiments on challenging multi-hop QA benchmarks, including HotpotQA, 2WikiMultiHopQA, and MusiQue. In a unified experimental setup, FAIR-RAG significantly outperforms strong baselines. On HotpotQA, it achieves an F1-score of 0.453 -- an absolute improvement of 8.3 points over the strongest iterative baseline -- establishing a new state-of-the-art for this class of methods on these benchmarks. Our work demonstrates that a structured, evidence-driven refinement process with explicit gap analysis is crucial for unlocking reliable and accurate reasoning in advanced RAG systems for complex, knowledge-intensive tasks.

Datasets play a critical role in medical imaging research, yet issues such as label quality, shortcuts, and metadata are often overlooked. This lack of attention may harm the generalizability of algorithms and, consequently, negatively impact patient outcomes. While existing medical imaging literature reviews mostly focus on machine learning (ML) methods, with only a few focusing on datasets for specific applications, these reviews remain static -- they are published once and not updated thereafter. This fails to account for emerging evidence, such as biases, shortcuts, and additional annotations that other researchers may contribute after the dataset is published. We refer to these newly discovered findings of datasets as research artifacts. To address this gap, we propose a living review that continuously tracks public datasets and their associated research artifacts across multiple medical imaging applications. Our approach includes a framework for the living review to monitor data documentation artifacts, and an SQL database to visualize the citation relationships between research artifact and dataset. Lastly, we discuss key considerations for creating medical imaging datasets, review best practices for data annotation, discuss the significance of shortcuts and demographic diversity, and emphasize the importance of managing datasets throughout their entire lifecycle. Our demo is publicly available at http://inthepicture.itu.dk/.

To improve the quality and efficiency of research, groups within the scientific community seek to exploit the value of data sharing. Funders, institutions, and specialist organizations are developing and implementing strategies to encourage or mandate data sharing within and across disciplines, with varying degrees of success. Academic journals in ecology and evolution have adopted several types of public data archiving policies requiring authors to make data underlying scholarly manuscripts freely available. Yet anecdotes from the community and studies evaluating data availability suggest that these policies have not obtained the desired effects, both in terms of quantity and quality of available datasets. We conducted a qualitative, interview-based study with journal editorial staff and other stakeholders in the academic publishing process to examine how journals enforce data archiving policies. We specifically sought to establish who editors and other stakeholders perceive as responsible for ensuring data completeness and quality in the peer review process. Our analysis revealed little consensus with regard to how data archiving policies should be enforced and who should hold authors accountable for dataset submissions. Themes in interviewee responses included hopefulness that reviewers would take the initiative to review datasets and trust in authors to ensure the completeness and quality of their datasets. We highlight problematic aspects of these thematic responses and offer potential starting points for improvement of the public data archiving process.

Safety alignment in Large Language Models is critical for healthcare; however, reliance on binary refusal boundaries often results in over-refusal of benign queries or unsafe compliance with harmful ones. While existing benchmarks measure these extremes, they fail to evaluate Safe Completion: the model's ability to maximise helpfulness on dual-use or borderline queries by providing safe, high-level guidance without crossing into actionable harm. We introduce Health-ORSC-Bench, the first large-scale benchmark designed to systematically measure Over-Refusal and Safe Completion quality in healthcare. Comprising 31,920 benign boundary prompts across seven health categories (e.g., self-harm, medical misinformation), our framework uses an automated pipeline with human validation to test models at varying levels of intent ambiguity. We evaluate 30 state-of-the-art LLMs, including GPT-5 and Claude-4, revealing a significant tension: safety-optimised models frequently refuse up to 80\% of "Hard" benign prompts, while domain-specific models often sacrifice safety for utility. Our findings demonstrate that model family and size significantly influence calibration: larger frontier models (e.g., GPT-5, Llama-4) exhibit "safety-pessimism" and higher over-refusal than smaller or MoE-based counterparts (e.g., Qwen-3-Next), highlighting that current LLMs struggle to balance refusal and compliance. Health-ORSC-Bench provides a rigorous standard for calibrating the next generation of medical AI assistants toward nuanced, safe, and helpful completions. The code and data will be released upon acceptance. red{Warning: Some contents may include toxic or undesired contents.}

Claim verification is critical for enhancing digital literacy. However, the state-of-the-art single-LLM methods struggle with complex claim verification that involves multi-faceted evidences. Inspired by real-world fact-checking practices, we propose DebateCV, the first claim verification framework that adopts a debate-driven methodology using multiple LLM agents. In our framework, two Debaters take opposing stances on a claim and engage in multi-round argumentation, while a Moderator evaluates the arguments and renders a verdict with justifications. To further improve the performance of the Moderator, we introduce a novel post-training strategy that leverages synthetic debate data generated by the zero-shot DebateCV, effectively addressing the scarcity of real-world debate-driven claim verification data. Experimental results show that our method outperforms existing claim verification methods under varying levels of evidence quality. Our code and dataset are publicly available at https://anonymous.4open.science/r/DebateCV-6781.

Ensuring that Large Language Models (LLMs) generate summaries faithful to a given source document is essential for real-world applications. While prior research has explored LLM faithfulness, existing benchmarks suffer from annotation ambiguity, primarily due to the ill-defined boundary of permissible external knowledge in generated outputs. For instance, common sense is often incorporated into responses and labeled as "faithful", yet the acceptable extent of such knowledge remains unspecified, leading to inconsistent annotations. To address this issue, we propose a novel faithfulness annotation framework, which introduces an intermediate category, Out-Dependent, to classify cases where external knowledge is required for verification. Using this framework, we construct VeriGray (Verification with the Gray Zone) -- a new unfaithfulness detection benchmark in summarization. Statistics reveal that even SOTA LLMs, such as GPT-5, exhibit hallucinations (sim 6% of sentences) in summarization tasks. Moreover, a substantial proportion (sim 8% on average of models) of generated sentences fall into the Out-Dependent category, underscoring the importance of resolving annotation ambiguity in unfaithfulness detection benchmarks. Experiments demonstrate that our benchmark poses significant challenges to multiple baseline methods, indicating considerable room for future improvement.

Large Language Models (LLMs) have emerged as promising assistants for scientific writing. However, there have been concerns regarding the quality and reliability of the generated text, one of which is the citation accuracy and faithfulness. While most recent work relies on methods such as LLM-as-a-Judge, the reliability of LLM-as-a-Judge alone is also in doubt. In this work, we reframe citation evaluation as a problem of citation attribution alignment, which is assessing whether LLM-generated citations match those a human author would include for the same text. We propose CiteGuard, a retrieval-aware agent framework designed to provide more faithful grounding for citation validation. CiteGuard improves the prior baseline by 12.3%, and achieves up to 65.4% accuracy on the CiteME benchmark, on par with human-level performance (69.7%). It also enables the identification of alternative but valid citations.

The core premise of AI debate as a scalable oversight technique is that it is harder to lie convincingly than to refute a lie, enabling the judge to identify the correct position. Yet, existing debate experiments have relied on datasets with ground truth, where lying is reduced to defending an incorrect proposition. This overlooks a subjective dimension: lying also requires the belief that the claim defended is false. In this work, we apply debate to subjective questions and explicitly measure large language models' prior beliefs before experiments. Debaters were asked to select their preferred position, then presented with a judge persona deliberately designed to conflict with their identified priors. This setup tested whether models would adopt sycophantic strategies, aligning with the judge's presumed perspective to maximize persuasiveness, or remain faithful to their prior beliefs. We implemented and compared two debate protocols, sequential and simultaneous, to evaluate potential systematic biases. Finally, we assessed whether models were more persuasive and produced higher-quality arguments when defending positions consistent with their prior beliefs versus when arguing against them. Our main findings show that models tend to prefer defending stances aligned with the judge persona rather than their prior beliefs, sequential debate introduces significant bias favoring the second debater, models are more persuasive when defending positions aligned with their prior beliefs, and paradoxically, arguments misaligned with prior beliefs are rated as higher quality in pairwise comparison. These results can inform human judges to provide higher-quality training signals and contribute to more aligned AI systems, while revealing important aspects of human-AI interaction regarding persuasion dynamics in language models.

The proliferation of online misinformation has posed significant threats to public interest. While numerous online users actively participate in the combat against misinformation, many of such responses can be characterized by the lack of politeness and supporting facts. As a solution, text generation approaches are proposed to automatically produce counter-misinformation responses. Nevertheless, existing methods are often trained end-to-end without leveraging external knowledge, resulting in subpar text quality and excessively repetitive responses. In this paper, we propose retrieval augmented response generation for online misinformation (RARG), which collects supporting evidence from scientific sources and generates counter-misinformation responses based on the evidences. In particular, our RARG consists of two stages: (1) evidence collection, where we design a retrieval pipeline to retrieve and rerank evidence documents using a database comprising over 1M academic articles; (2) response generation, in which we align large language models (LLMs) to generate evidence-based responses via reinforcement learning from human feedback (RLHF). We propose a reward function to maximize the utilization of the retrieved evidence while maintaining the quality of the generated text, which yields polite and factual responses that clearly refutes misinformation. To demonstrate the effectiveness of our method, we study the case of COVID-19 and perform extensive experiments with both in- and cross-domain datasets, where RARG consistently outperforms baselines by generating high-quality counter-misinformation responses.

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that report single or coarse-grained metrics are lack the granularity required for specialized clinical support and fail to assess the reliability of reasoning mechanisms. To address this, we propose a paradigm shift toward multidimensional, fine-grained and in-depth evaluation. Based on a two-stage systematic construction pipeline designed for this paradigm, we instantiate it with MedRCube. We benchmark 33 MLLMs, Lingshu-32B achieve top-tier performance. Crucially, MedRCube exposes a series of pronounced insights inaccessible under prior evaluation settings. Furthermore, we introduce a credibility evaluation subset to quantify reasoning credibility, uncover a highly significant positive association between shortcut behavior and diagnostic task performance, raising concerns for clinically trustworthy deployment. The resources of this work can be found at https://github.com/F1mc/MedRCube.

Ensuring alignment, which refers to making models behave in accordance with human intentions [1,2], has become a critical task before deploying large language models (LLMs) in real-world applications. For instance, OpenAI devoted six months to iteratively aligning GPT-4 before its release [3]. However, a major challenge faced by practitioners is the lack of clear guidance on evaluating whether LLM outputs align with social norms, values, and regulations. This obstacle hinders systematic iteration and deployment of LLMs. To address this issue, this paper presents a comprehensive survey of key dimensions that are crucial to consider when assessing LLM trustworthiness. The survey covers seven major categories of LLM trustworthiness: reliability, safety, fairness, resistance to misuse, explainability and reasoning, adherence to social norms, and robustness. Each major category is further divided into several sub-categories, resulting in a total of 29 sub-categories. Additionally, a subset of 8 sub-categories is selected for further investigation, where corresponding measurement studies are designed and conducted on several widely-used LLMs. The measurement results indicate that, in general, more aligned models tend to perform better in terms of overall trustworthiness. However, the effectiveness of alignment varies across the different trustworthiness categories considered. This highlights the importance of conducting more fine-grained analyses, testing, and making continuous improvements on LLM alignment. By shedding light on these key dimensions of LLM trustworthiness, this paper aims to provide valuable insights and guidance to practitioners in the field. Understanding and addressing these concerns will be crucial in achieving reliable and ethically sound deployment of LLMs in various applications.

Training expert LLMs in domains with scarce data is difficult, often relying on multiple-choice questions (MCQs). However, standard outcome-based reinforcement learning (RL) on MCQs is risky. While it may improve accuracy, we observe it often degrades reasoning quality such as logical consistency. Existing solutions to supervise reasoning, such as large-scale Process Reward Models (PRMs), are prohibitively expensive. To address this, we propose CLARity, a cost-effective RL framework that enhances reasoning quality using only a small, general-purpose LLM. CLARity integrates a consistency-aware reward mechanism with a 2-stage refine-then-monitor training pipeline to enhance reasoning consistency, and a dynamic data reformulation strategy to to better exploit limited data. Experiments demonstrate that CLARity improves response consistency by 16.5% and accuracy by 7.5% over baselines. Human evaluations further confirm holistic improvements in coherence and professionalism. Thus, CLARity offers a generalizable solution that enables smaller models to effectively guide expert models by reasoning consistency.Our code is open sourced at: https://github.com/Infinite-set/CLARity

Large Language Models (LLMs) offer natural language explanations as an alternative to feature attribution methods for model interpretability. However, despite their plausibility, they may not reflect the model's internal reasoning faithfully, which is crucial for understanding the model's true decision-making processes. Although several faithfulness metrics have been proposed, a unified evaluation framework remains absent. To address this gap, we present Causal Diagnosticity, a framework to evaluate faithfulness metrics for natural language explanations. Our framework employs the concept of causal diagnosticity, and uses model-editing methods to generate faithful-unfaithful explanation pairs. Our benchmark includes four tasks: fact-checking, analogy, object counting, and multi-hop reasoning. We evaluate a variety of faithfulness metrics, including post-hoc explanation and chain-of-thought-based methods. We find that all tested faithfulness metrics often fail to surpass a random baseline. Our work underscores the need for improved metrics and more reliable interpretability methods in LLMs.

Language Models (LMs) are being proposed for mental health applications where the heightened risk of adverse outcomes means predictive performance may not be a sufficient litmus test of a model's utility in clinical practice. A model that can be trusted for practice should have a correspondence between explanation and clinical determination, yet no prior research has examined the attention fidelity of these models and their effect on ground truth explanations. We introduce an evaluation design that focuses on the robustness and explainability of LMs in identifying Wellness Dimensions (WDs). We focus on two existing mental health and well-being datasets: (a) Multi-label Classification-based MultiWD, and (b) WellXplain for evaluating attention mechanism veracity against expert-labeled explanations. The labels are based on Halbert Dunn's theory of wellness, which gives grounding to our evaluation. We reveal four surprising results about LMs/LLMs: (1) Despite their human-like capabilities, GPT-3.5/4 lag behind RoBERTa, and MedAlpaca, a fine-tuned LLM on WellXplain fails to deliver any remarkable improvements in performance or explanations. (2) Re-examining LMs' predictions based on a confidence-oriented loss function reveals a significant performance drop. (3) Across all LMs/LLMs, the alignment between attention and explanations remains low, with LLMs scoring a dismal 0.0. (4) Most mental health-specific LMs/LLMs overlook domain-specific knowledge and undervalue explanations, causing these discrepancies. This study highlights the need for further research into their consistency and explanations in mental health and well-being.

Large Language Models (LLMs) often exhibit significant behavioral shifts when they perceive a change from a real-world deployment context to a controlled evaluation setting, a phenomenon known as "evaluation awareness." This discrepancy poses a critical challenge for AI alignment, as benchmark performance may not accurately reflect a model's true safety and honesty. In this work, we systematically quantify these behavioral changes by manipulating the perceived context of prompts. We introduce a methodology that uses a linear probe to score prompts on a continuous scale from "test-like" to "deploy-like" and leverage an LLM rewriting strategy to shift these prompts towards a more natural, deployment-style context while preserving the original task. Using this method, we achieved a 30% increase in the average probe score across a strategic role-playing dataset after rewriting. Evaluating a suite of state-of-the-art models on these original and rewritten prompts, we find that rewritten "deploy-like" prompts induce a significant and consistent shift in behavior. Across all models, we observed an average increase in honest responses of 5.26% and a corresponding average decrease in deceptive responses of 12.40%. Furthermore, refusal rates increased by an average of 6.38%, indicating heightened safety compliance. Our findings demonstrate that evaluation awareness is a quantifiable and manipulable factor that directly influences LLM behavior, revealing that models are more prone to unsafe or deceptive outputs in perceived test environments. This underscores the urgent need for more realistic evaluation frameworks to accurately gauge true model alignment before deployment.

Despite growing interest in using large language models (LLMs) in healthcare, current explorations do not assess the real-world utility and safety of LLMs in clinical settings. Our objective was to determine whether two LLMs can serve information needs submitted by physicians as questions to an informatics consultation service in a safe and concordant manner. Sixty six questions from an informatics consult service were submitted to GPT-3.5 and GPT-4 via simple prompts. 12 physicians assessed the LLM responses' possibility of patient harm and concordance with existing reports from an informatics consultation service. Physician assessments were summarized based on majority vote. For no questions did a majority of physicians deem either LLM response as harmful. For GPT-3.5, responses to 8 questions were concordant with the informatics consult report, 20 discordant, and 9 were unable to be assessed. There were 29 responses with no majority on "Agree", "Disagree", and "Unable to assess". For GPT-4, responses to 13 questions were concordant, 15 discordant, and 3 were unable to be assessed. There were 35 responses with no majority. Responses from both LLMs were largely devoid of overt harm, but less than 20% of the responses agreed with an answer from an informatics consultation service, responses contained hallucinated references, and physicians were divided on what constitutes harm. These results suggest that while general purpose LLMs are able to provide safe and credible responses, they often do not meet the specific information need of a given question. A definitive evaluation of the usefulness of LLMs in healthcare settings will likely require additional research on prompt engineering, calibration, and custom-tailoring of general purpose models.

A promising approach for improving reasoning in large language models is to use process reward models (PRMs). PRMs provide feedback at each step of a multi-step reasoning trace, potentially improving credit assignment over outcome reward models (ORMs) that only provide feedback at the final step. However, collecting dense, per-step human labels is not scalable, and training PRMs from automatically-labeled data has thus far led to limited gains. To improve a base policy by running search against a PRM or using it as dense rewards for reinforcement learning (RL), we ask: "How should we design process rewards?". Our key insight is that, to be effective, the process reward for a step should measure progress: a change in the likelihood of producing a correct response in the future, before and after taking the step, corresponding to the notion of step-level advantages in RL. Crucially, this progress should be measured under a prover policy distinct from the base policy. We theoretically characterize the set of good provers and our results show that optimizing process rewards from such provers improves exploration during test-time search and online RL. In fact, our characterization shows that weak prover policies can substantially improve a stronger base policy, which we also observe empirically. We validate our claims by training process advantage verifiers (PAVs) to predict progress under such provers, and show that compared to ORMs, test-time search against PAVs is >8% more accurate, and 1.5-5times more compute-efficient. Online RL with dense rewards from PAVs enables one of the first results with 5-6times gain in sample efficiency, and >6% gain in accuracy, over ORMs.

Writing effective rebuttals is a high-stakes task that demands more than linguistic fluency, as it requires precise alignment between reviewer intent and manuscript details. Current solutions typically treat this as a direct-to-text generation problem, suffering from hallucination, overlooked critiques, and a lack of verifiable grounding. To address these limitations, we introduce RebuttalAgent, the first multi-agents framework that reframes rebuttal generation as an evidence-centric planning task. Our system decomposes complex feedback into atomic concerns and dynamically constructs hybrid contexts by synthesizing compressed summaries with high-fidelity text while integrating an autonomous and on-demand external search module to resolve concerns requiring outside literature. By generating an inspectable response plan before drafting, RebuttalAgent ensures that every argument is explicitly anchored in internal or external evidence. We validate our approach on the proposed RebuttalBench and demonstrate that our pipeline outperforms strong baselines in coverage, faithfulness, and strategic coherence, offering a transparent and controllable assistant for the peer review process. Code will be released.

Despite substantial progress in fact-verification benchmarks, claims grounded in large-scale structured data remain underexplored. In this work, we introduce ClaimDB, the first fact-verification benchmark where the evidence for claims is derived from compositions of millions of records and multiple tables. ClaimDB consists of 80 unique real-life databases covering a wide range of domains, from governance and healthcare to media, education and the natural sciences. At this scale, verification approaches that rely on "reading" the evidence break down, forcing a timely shift toward reasoning in executable programs. We conduct extensive experiments with 30 state-of-the-art proprietary and open-source (below 70B) LLMs and find that none exceed 83% accuracy, with more than half below 55%. Our analysis also reveals that both closed- and open-source models struggle with abstention -- the ability to admit that there is no evidence to decide -- raising doubts about their reliability in high-stakes data analysis. We release the benchmark, code, and the LLM leaderboard at https://claimdb.github.io .

Recent advances in large language models have enabled deep research systems that generate expert-level reports through multi-step reasoning and evidence-based synthesis. However, evaluating such reports remains challenging: report quality is multifaceted, making it difficult to determine what to assess and by what criteria; LLM-based judges may miss errors that require domain expertise to identify; and because deep research relies on retrieved evidence, report-wide claim verification is also necessary. To address these issues, we propose DEER, a benchmark for evaluating expert-level deep research reports. DEER systematizes evaluation criteria with an expert-developed taxonomy (7 dimensions, 25 subdimensions) operationalized as 101 fine-grained rubric items. We also provide task-specific Expert Evaluation Guidance to support LLM-based judging. Alongside rubric-based assessment, we propose a claim verification architecture that verifies both cited and uncited claims and quantifies evidence quality. Experiments show that while current deep research systems can produce structurally plausible reports that cite external evidence, there is room for improvement in fulfilling expert-level user requests and achieving logical completeness. Beyond simple performance comparisons, DEER makes system strengths and limitations interpretable and provides diagnostic signals for improvement.

This position paper argues that the theoretical inconsistency often observed among Responsible AI (RAI) metrics, such as differing fairness definitions or tradeoffs between accuracy and privacy, should be embraced as a valuable feature rather than a flaw to be eliminated. We contend that navigating these inconsistencies, by treating metrics as divergent objectives, yields three key benefits: (1) Normative Pluralism: Maintaining a full suite of potentially contradictory metrics ensures that the diverse moral stances and stakeholder values inherent in RAI are adequately represented. (2) Epistemological Completeness: The use of multiple, sometimes conflicting, metrics allows for a more comprehensive capture of multifaceted ethical concepts, thereby preserving greater informational fidelity about these concepts than any single, simplified definition. (3) Implicit Regularization: Jointly optimizing for theoretically conflicting objectives discourages overfitting to one specific metric, steering models towards solutions with enhanced generalization and robustness under real-world complexities. In contrast, efforts to enforce theoretical consistency by simplifying or pruning metrics risk narrowing this value diversity, losing conceptual depth, and degrading model performance. We therefore advocate for a shift in RAI theory and practice: from getting trapped in inconsistency to characterizing acceptable inconsistency thresholds and elucidating the mechanisms that permit robust, approximated consistency in practice.